October 31, 2014
CORONADO, Calif. — A survival benefit was found among patients with differentiated thyroid carcinoma who underwent total/near-total thyroidectomy followed by radioactive iodine therapy, according to study findings presented here.
“To date there are no prospective studies evaluating the longitudinal effects of initial long-term therapy in differentiated thyroid cancer. … The challenge for clinicians becomes balancing the potential risks of more aggressive therapy — such as aggressive thyroid hormone suppression — and the risks associated with long-term thyrotoxicosis with the potential benefits of treatment. This is not always clear, especially in patients who are at a variety of risks for cancer-specific mortality,” Aubrey A. Carhill, MD, of the University of Texas MD Anderson Cancer Center, said during her presentation. “There remains a need for accurate prognostication in order to identify which patients will benefit from different treatment modalities.”