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Higher CD8 T-cell dose from younger donors improves allogeneic HSCT outcomes

Higher CD8 T-cell dose from younger donors improves allogeneic HSCT outcomes
July 2, 2015

A higher graft CD8 dose from younger donors — even if they are not related to the patient — predicted improved survival in patients with hematologic malignancies undergoing reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation, according to study results.

Further, a blood test to measure the T lymphocyte count in donors may help identify the best donor match for patients undergoing hematopoietic stem cell transplant (HSCT), the researchers found.

In the Journals

Clonal hematopoiesis common, variable in patients with aplastic anemia

July 2, 2015
Clonal hematopoiesis commonly occurs in patients with aplastic anemia, according to study results. Although detected somatic mutations were associated with clinical…
Petros Grivas, MD, PhD Meeting News Coverage

Top Takeaways from ASCO: Urothelial Cancer

July 1, 2015
CHICAGO — Data on two immune checkpoint inhibitors for the treatment of urothelial cancer represent important findings for this type of cancer presented at the…
In the Journals

Indoor tanning rates drop in US adults between 2010 and 2013

July 1, 2015
Indoor tanning rates have dropped among adults in the United States between 2010 and 2013, according to recently published study results.Researchers analyzed National…
Anna E. Coghill, PhD, MPH In the Journals

HIV increases risk for death from common cancers

July 1, 2015
Patients with cancer who are HIV-infected experienced significantly higher cancer mortality rates compared with patients without HIV, according to study…
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Tailored Therapies for Myelodysplastic Syndromes

Tailored Therapies for Myelodysplastic Syndromes

This activity is supported by an educational grant from Celgene Corporation.

Myelodysplastic syndromes (MDS) represent a group of myeloid clonal hemopathies with heterogeneous clinical…
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Meeting News Coverage Video
VIDEO: Complete lymph node dissection does not improve outcomes in SLNB-positive melanoma

VIDEO: Complete lymph node dissection does not improve outcomes in SLNB-positive melanoma

June 19, 2015
CHICAGO — Vernon K. Sondak, MD, chair of the department of cutaneous oncology at Moffitt Cancer Center and a…
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CME CNE
Low Risk AAMDS

Treatment Decision-Making through the Spectrum of MDS:
Case 1 Low Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain MDS…
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