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Matched tumor analyses leads to more accurate diagnoses

May 29, 2015

Sequencing normal tissue besides tumor tissue resulted in more accurate identification and interpretation of somatic and germline alterations that could inform treatment plans for patients with cancer, according to the results of a retrospective analysis.

Matched tumor-normal sequencing analyses led to the identification of somatic alterations in genes associated with therapies or clinical trials in three-quarters of patients with somatic mutations; however, tumor-only sequencing was associated with a 31% to 65% false-positive rate.

In the Journals

Systemic therapy underutilized in NSCLC treatment, particularly among older patients

May 28, 2015
Most patients with metastatic non–small cell lung cancer in the general population did not receive systemic therapy, especially if they were older or had squamous…
Robert H.I. Andtbacka, MD In the JournalsPerspective

Higher response rate seen with T-VEC in advanced melanoma

May 28, 2015
Patients with unresected stage IIIB to IV melanoma who were treated with talimogene laherparepvec experienced a higher durable response rate than patients treated with…
In the Journals

Pharmacist-managed medication refill clinics ease physician workload

May 28, 2015
Establishing a pharmacist-managed medication refill clinic decreased workloads for physicians, and improved refill-request processing time and patient care, according to…
In the Journals

Serial biomarker levels may better detect epithelial ovarian cancer

May 28, 2015
Monitoring changes in annual serum cancer antigen 125 levels could detect twice the number of women with invasive epithelial ovarian cancer compared with standard…
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Stem Cell Transplant for AAMDS

Treatment Decision-Making through the Spectrum of MDS:
Case 3 Stem Cell Transplant for MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
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Meeting News Coverage Video
VIDEO: Updates in prostate cancer treatment options

VIDEO: Updates in prostate cancer treatment options

May 5, 2015
Robert S. DiPaola, MD, director of Rutgers Cancer Institute of New Jersey, discusses various forms of prostate cancer…
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Hematology Oncology Case Consults

The Patient with Melanoma

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with melanoma.
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