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APRI, FIB4 guide esophageal varices screening in light of hemophilia, coinfection

February 22, 2017

The aspartate transaminase-platelet ratio index and Fibrosis-4 score were effective non-invasive markers to monitor fibrosis and correlated to the presence of esophageal varices in hemophilic patients coinfected with HIV and hepatitis C, according to a new study.

“The use of such non-invasive and simple markers to check liver fibrosis is especially important in hemophilic patients, in whom liver biopsies should be avoided because of the possible hemorrhagic complication,” the researchers wrote. “It appears that APRI and FIB4 are good indicators for monitoring not only liver fibrosis but also esophageal varices, and we therefore strongly recommend that endoscopy be carried out when patients show an APRI or FIB4 value over the cut-off value described in this study.”

Novel probe has potential to aid in margin detection during cancer surgery

February 22, 2017
Researchers in Australia have developed a novel optical fiber probe with high sensitivity for detecting and differentiating cancerous tissue from healthy tissue in…

Many patients lack knowledge about advances in cancer diagnostics, treatment

February 22, 2017
A majority of patients with cancer and their caregivers lack sufficient knowledge about advances in diagnostic and treatment options, according to results of a survey…

Monoclonal antibodies show promise in treating solid tumors

HemOnc Today, February 25, 2017
Tremendous excitement currently surrounds the use of immuno-oncology agents for the treatment of various of solid tumors. Immuno-oncology treatments – including…
In the Journals Plus

Neoadjuvant therapy improves breast cancer recurrence rates among African American women

February 22, 2017
Neoadjuvant chemotherapy improved prognosis and recurrence rates of breast cancer among African American patients, according to findings published in PLoS One.
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Toward Precision Medicine for Advanced Melanoma Management: Making the Most of Targeted Agents

This activity is supported by an educational grant from Novartis.

The identification and utilization of melanoma specific biomarkers continues to be of importance for diagnosis and…
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Meeting News

VIDEO: Down syndrome does not affect management of pediatric ALL

January 5, 2017
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Management of Multiple Myeloma: Using Emerging Therapies with ASCT

This activity is supported by educational grants from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; Spectrum Pharmaceuticals, Inc.; and Takeda Oncology.

Multiple myeloma management has undergone profound changes in the past few decades, this is largely due to advances in…
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