Hematology/Oncology

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Plasma analysis shows promise for NSCLC T790M genotyping

Plasma analysis shows promise for NSCLC <i>T790M</i> genotyping
August 23, 2016

Patients with T790M–positive advanced non–small cell lung cancer demonstrated similar outcomes with osimertinib whether the T790M mutation was detected using plasma analysis or a tissue-based assay, according to a retrospective analysis of the AURA trial.

Thus, plasma analysis may provide a less invasive diagnostic alternative to undergoing a tumor biopsy to detect acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors, according to the researchers.

In the Journals

TAVR survival rate similar in patients with aortic stenosis, cancer vs. no cancer

August 23, 2016
Patients with severe aortic stenosis and active cancer who undergo transcatheter aortic valve replacement had comparable survival rates compared with patients with
FDA News

FDA grants priority review to rucaparib for advanced BRCA–mutated ovarian cancer

August 23, 2016
The FDA granted priority review to rucaparib for the treatment of advanced ovarian cancer in patients with germline or somatic BRCA–mutated tumors. The…
In the Journals Plus

Corticosteroids, immune globulin induce similar platelet count responses for ITP during pregnancy

August 23, 2016
Pregnant women with immune thrombocytopenia had similar maternal platelet count responses whether treated with IV immune globulin or corticosteroids, according to the…
In the Journals Plus

Power morcellation use declines following FDA safety warning

August 23, 2016
The use of power morcellation among women undergoing minimally invasive hysterectomy significantly decreased in the wake of an FDA recommendation against its use…
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CME

Updates from Vienna 2015 – Highlights in Hematologic Malignancies

This activity is supported by an educational grant from Genentech, Inc.

The management of patients with hematologic malignancies—from diagnosis to treatment decisions—can represent a…
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Video
Meeting News Coverage

VIDEO: Checkpoint inhibitors, vaccines, viral therapy may offer multiple treatment options for brain tumors

August 16, 2016
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Discoveries from ASCO 2016: Breast Cancer

Discoveries from ASCO 2016: Breast Cancer

CME

Optimizing the Use of Targeted Therapy in Advanced Melanoma: Where We Are and Where We Are Going

This activity is supported by an educational grant from Genentech.

Melanoma is the deadliest form of skin cancer. Historically, treatment options have been limited for patients with…
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