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Chronic fungal lesions predisposed to malignancy

March 2, 2015

Researchers in Brazil documented seven cases of squamous cell carcinoma that resulted from chronic chromoblastomycosis in the Brazilian Amazon state Maranhão.

“There appears to be remarkable polymorphism in the presentation of [chromoblastomycosis] lesions, where the most aggressive and disabling manifestation is possible malignant transformation,” the researchers wrote in Clinical Infectious Diseases. “However, this extreme is considered rare by some authors, probably due to the lower number of reports to date. Here we demonstrate that malignancy may be more common in [chromoblastomycosis] than shown by current data.”

In the JournalsPerspective

Recursive partitioning analysis forms new stages for HPV-related oropharyngeal cancer

March 2, 2015
Recursive partitioning analysis-based TNM stage groupings were associated with significantly improved survival prediction for patients with HPV-related non-metastatic…
Deepa Bhojwani, MD Institution Notes

Childrens hospital appoints leukemia director

March 1, 2015
Deepa Bhojwani, MD, has been appointed director of the leukemia/lymphoma program at the Children’s Center for Cancer and Blood Diseases, part of Children’s…
Institution Notes

NIH recruits three Lasker scholars

February 28, 2015
The NIH has selected three researchers as new Lasker Clinical Research Scholars as part of a joint initiative with the Albert and Mary Lasker Foundation to nurture the…
In the Journals

Combination of trastuzumab, XELOX shows promise for advanced gastric cancer

February 27, 2015
The addition of trastuzumab to the standard first-line regimen of capecitabine plus oxaliplatin created a highly effective and well-tolerated combination for the…
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Hot melanoma

Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates - Monograph

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
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MET targeting, PD-L1/PD-1 inhibition highlight recent developments in genitourinary oncology

February 11, 2015
Derek Raghavan, MD, PhD, FACP, FRACP, FASCO, president of Levine Cancer Institute at Carolinas HealthCare System and…
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High Risk AAMDS

Treatment Decision-Making through the Spectrum of MDS:
Case 2 High Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
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