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History of cancer cited among risk factors for failure of flap coverage in revision TKA

March 27, 2015

LAS VEGAS — A retrospective review presented here of 43 flaps used for coverage of soft tissue defects in revision total knee arthroplasty identifies risk factors for flap failure and found 37.2% of flaps were removed and revised with another flap or were involved in a below-the-knee amputation at a mean of 16.5 months.  

“Soft tissue coverage in revision total knee arthroplasty (TKA) poses serious challenges,” Bishoy V. Gad, MD, said at the American Academy of Orthopaedic Surgeons Annual Meeting.  “Patients with a history of cancer, heart failure or Klebsiella infection have higher odds of failure, and patients with a history of cancer or Klebsiella are at an increased risk of diminished survival.”   

In the Journals

Carboplatin noninferior to cisplatin for metastatic, recurrent cervical cancer

March 26, 2015
Carboplatin-based chemotherapy should be a standard treatment option for metastatic or recurrent cervical cancer, according to findings from a randomized phase 3…
FDA News

FDA grants orphan drug designation to sevuparin for sickle cell disease

March 26, 2015
The FDA granted orphan drug designation to sevuparin for the treatment of patients with sickle cell disease, according to a press release from the drug’s…

Botswana-UPenn partnership, Microsoft to launch telemedicine service in Botswana

March 26, 2015
The Botswana-UPenn Partnership, along with Microsoft, the Botswana Innovation Hub, and others are planning to launch the first telemedicine service in Africa…
Breaking News

House passes bill to repeal sustainable growth rate

March 26, 2015
By a vote of 392 to 37, the U.S. House of Representatives passed a bipartisan bill today that repeals the sustainable growth rate, a key factor in annual Medicare…
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New Advances, New Options: Evaluating the Changing Landscape of Hemophilia

New Advances, New Options: Evaluating the Changing Landscape of Hemophilia to Optimize Patient Outcomes

This activity is supported by an educational grant from Biogen Idec.

The bleeding abnormalities associated with hemophilia can have devastating consequences for patients. Recent advances…
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3D printing has applications, challenges in a variety of medical specialties

March 20, 2015
SAN FRANCISCO — Scott Hollister, PhD, professor of biomedical engineering at the University of Michigan, talks…
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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates

This activity is supported by an educational grant from Merck & Co., Inc.

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
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