October 13, 2015
Long-term circulating platinum exposures corresponded with known late effects such as paraesthesia, hypogonadism, high cholesterol and hypertension among chemotherapy-treated survivors of testicular cancer, according to study results.
“Since the introduction of platinum-based chemotherapy, metastatic testicular cancer has become a curable disease with an excellent prognosis,” Jourik A. Gietema, MD, professor of medical oncology at University of Groningen in the Netherlands, and colleagues wrote. “However, late effects of the treatment may compromise the quality of life after treatment. … A decade ago, Gietema and colleagues found that long-term circulating platinum levels remained detectable up to 20 years after cisplatin combination chemotherapy.”