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Artificial hybrid likely required for treating giant cell tumor of bone with zoledronic acid

January 29, 2015

In a recently published study, researchers determined that to effectively treat giant cell tumors of bone with zoledronic acid, a hybrid including artificial bone would be needed.

The researchers evaluated five patients with giant cell tumor of bone treated with zoledronic acid between 2008 and 2013 at a single institution. The tumors were either grade II or III on the Campanacci scale. Four patients received zoledronic acid with artificial bone, and one patient was administered the treatment without it. Surgically resected specimens were utilized to determine the patients’ histologic response.

FDA News

FDA expands approval of Imbruvica to treat Waldenström's macroglobulinemia

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The FDA today announced the expanded approval of ibrutinib for the treatment of Waldenström’s macroglobulinemia, a rare form of non-Hodgkin’s lymphoma…
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Biomarkers predicted severity of GVHD after allogenic HSCT

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A prognostic score based on the concentration of biomarkers guided risk-adapted therapy at the onset of graft-versus-host disease following allogeneic hematopoietic stem…
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Pemetrexed benefited lung cancer patients with ALK mutations

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Patients with lung adenocarcinoma who have anaplastic lymphoma kinase gene mutations derived greater benefit from pemetrexed-based therapy than those without the…
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Ruxolitinib superior to standard therapy for polycythemia vera

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Meeting News Coverage Video
Genome editing demonstrated wide application for blood disorders

Genome editing demonstrated wide application for blood disorders

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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates

This activity is supported by an educational grant from Merck & Co., Inc.

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