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High AKR1B10 protein expression showed promising survival rates for HCC

December 18, 2014

Among a cohort of Korean patients with hepatocellular carcinoma, high aldo-keto reductase 1B10 protein expression predicted longer recurrence-free and disease-specific survival rates vs. patients with low protein expression.

Sang Yun Ha, MD, of Sungkyunkwan University School of Medicine in Korea, and colleagues used tissue microarrays to measure expression levels of aldo-keto reductase 1B10 (AKR1B10) protein in tumors of 255 patients with HCC who underwent curative hepatectomy to determine its effect on the survival of the patients during a median follow-up period of 119.8 months.

Ian Krop In the Journals

Ado-trastuzumab emtansine significantly extended OS in HER-2–positive breast cancer with CNS metastases

December 18, 2014
Patients with HER-2–positive advanced breast cancer treated with ado-trastuzumab emtansine experienced similar rates of central nervous system progression as those…
Meeting News CoveragePerspective

Early thymic precursor immunophenotype does not affect T-cell ALL outcomes

December 18, 2014
SAN FRANCISCO — Children with T-cell acute lymphoblastic leukemia achieved favorable 5-year EFS and OS outcomes regardless of whether they expressed the early…
Health Care Legislative and Regulatory Update

New year, new code: How to get paid for chronic care management in 2015, part 1

December 18, 2014
From international law firm Arnold & Porter LLP comes a timely column that provides views on current regulatory and legislative topics that weigh on the minds of today’s…
Six chemotherapy cycles failed to improve outcomes in node-negative breast cancer Meeting News Coverage

Six chemotherapy cycles failed to improve outcomes in node-negative breast cancer

December 18, 2014
SAN ANTONIO — Patients with node-negative breast cancer who received six cycles of 5-fluorouracil, epirubicin and cyclophosphamide experienced similar DFS and OS as…
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CME
New Advances, New Options: Evaluating the Changing Landscape of Hemophilia

New Advances, New Options: Evaluating the Changing Landscape of Hemophilia to Optimize Patient Outcomes

This activity is supported by an educational grant from Biogen Idec.

The bleeding abnormalities associated with hemophilia can have devastating consequences for patients. Recent advances…
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Meeting News Coverage Video
IBIS-I: Tamoxifen provides long-term protection for women at high risk for breast cancer

IBIS-I: Tamoxifen provides long-term protection for women at high risk for breast cancer

December 12, 2014
SAN ANTONIO — Erin W. Hofstatter, MD, director of the Breast Cancer Genetics and Prevention Program at Yale…
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CME CNE
Stem Cell Transplant for AAMDS

Treatment Decision-Making through the Spectrum of MDS:
Case 3 Stem Cell Transplant for MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
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