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IMRT reduced recurrence rates in primary soft tissue sarcoma

September 26, 2014

Patients with primary soft tissue sarcomas of the extremity who underwent intensity-modulated radiation therapy experienced significantly reduced rates of local recurrence compared with those who underwent conventional external beam radiation therapy, according to study results.

Adjuvant radiation therapy — known to improve local control for soft tissue sarcoma of the extremity following limb-sparing surgery — may be given via brachytherapy or external-beam radiation therapy (EBRT). EBRT options include conventional EBRT, intensity-modulated radiation therapy (IMRT) and proton therapy.

In the Journals

TH-302 demonstrates encouraging activity in soft tissue sarcoma

September 23, 2014
The investigational hypoxia-targeted drug TH-302 was associated with PFS, OS and tumor response rates that compared favorably with other first-line agents for soft…
In the Journals

Survivors of osteosarcoma at increased risk for second malignant neoplasms

August 28, 2014
Survivors of osteosarcoma demonstrated an increased risk for second malignant neoplasms, and the risk persisted long after the conclusion of osteosarcoma treatment…
In the Journals

Tumor size, location, grade predicted late recurrence in soft tissue sarcoma

August 6, 2014
Late recurrence in most patients treated for soft tissue sarcoma is uncommon, according to study results.However, the findings suggest long-term follow-up is necessary…
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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates - Monograph

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In the Journals

IMRT reduced recurrence rates in primary soft tissue sarcoma

September 26, 2014
Patients with primary soft tissue sarcomas of the extremity who underwent intensity-modulated radiation therapy experienced significantly reduced…
In the Journals

TH-302 demonstrates encouraging activity in soft tissue sarcoma

September 23, 2014
The investigational hypoxia-targeted drug TH-302 was associated with PFS, OS and tumor response rates that compared favorably with other first-line…
In the Journals

Survivors of osteosarcoma at increased risk for second malignant neoplasms

August 28, 2014
Survivors of osteosarcoma demonstrated an increased risk for second malignant neoplasms, and the risk persisted long after the conclusion of…
In the Journals

Tumor size, location, grade predicted late recurrence in soft tissue sarcoma

August 6, 2014
Late recurrence in most patients treated for soft tissue sarcoma is uncommon, according to study results.However, the findings suggest long-term…
FDA News

FDA accepts first application for biosimilar filgrastim

July 28, 2014
Sandoz Inc. recently announced that the FDA has accepted its Biologics License Application for filgrastim, which was filed under the new biosimilar…
In the Journals

Time to diagnosis not associated with survival in adolescents with Ewing tumors

June 27, 2014
The time to diagnosis of Ewing tumors was long and did not improve over time, but it did not appear to affect survival, surgical outcome or…

Top 8 lessons learned at ASCO 2014

June 25, 2014
The theme of this year’s ASCO Annual Meeting, “Science and Society,” emphasized patient-centered focus — looking at the full…
Perspective

Temsirolimus combination improved event-free survival in rhabdomyosarcoma

June 1, 2014
There are about 400 new cases of rhabdomyosarcoma diagnosed in children younger than 19 years in this country every year. Part of the clinical…
Meeting News Coverage Perspective

Risk-based strategy outlines new approach to treatment in pediatric soft tissue sarcomas

June 1, 2014
CHICAGO — A risk-based treatment strategy categorized pediatric patients with nonrhabdomyosarcoma soft tissue sarcomas into distinct prognostic…
In the Journals

Surgical resection of extremity tumors after chemotherapy brings better results

May 27, 2014
Surgical resection of a primary tumor in the extremities following neoadjuvant chemotherapy leads to more positive results, according to recently…
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