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Double-unit cord-blood transplant failed to extend survival in blood cancers

October 29, 2014

Children and adolescents with hematologic malignancies who underwent double-unit cord-blood transplantation experienced similar survival rates as those who underwent single-unit transplants, according to results of a phase 3 randomized trial.

However, patients who received a single unit of cord blood achieved better platelet recovery and demonstrated a reduced risk for grade III and grade IV acute and extensive chronic graft-versus-host disease (GVHD).

Institution Notes

Pediatric nurses’ association names president-elect

October 25, 2014
The Association of Pediatric Hematology/Oncology Nurses announced Kathleen Ruccione, PhD, MPH, RN, CPON, FAAN, will serve as president-elect for 2014-15.Ruccione…
Institution Notes

St. Jude announces faculty appointments

HemOnc Today, September 25, 2014
St. Jude Children’s Research Hospital officials announced the appointment of two internationally recognized physician–scientists to leadership positions.Mitchell Weiss
In the Journals

Primary tumor site affected clinical features, outcomes in pediatric neuroblastoma

September 19, 2014
Tumor features and outcomes varied considerably by primary tumor site among children with neuroblastoma, according to study results.Kieuhoa T. Vo, MD, of Benioff…
CME
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New Advances, New Options: Evaluating the Changing Landscape of Hemophilia to Optimize Patient Outcomes

This activity is supported by an educational grant from Biogen Idec.

The bleeding abnormalities associated with hemophilia can have devastating consequences for patients. Recent advances…
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CME
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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates

This activity is supported by an educational grant from Merck & Co., Inc.

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
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figure In the Journals

Double-unit cord-blood transplant failed to extend survival in blood cancers

October 29, 2014
Children and adolescents with hematologic malignancies who underwent double-unit cord-blood transplantation experienced similar survival rates as…
Institution Notes

Pediatric nurses’ association names president-elect

October 25, 2014
The Association of Pediatric Hematology/Oncology Nurses announced Kathleen Ruccione, PhD, MPH, RN, CPON, FAAN, will serve as president-elect for…
Institution Notes

St. Jude announces faculty appointments

HemOnc Today, September 25, 2014
St. Jude Children’s Research Hospital officials announced the appointment of two internationally recognized physician–scientists to leadership…
In the Journals

Primary tumor site affected clinical features, outcomes in pediatric neuroblastoma

September 19, 2014
Tumor features and outcomes varied considerably by primary tumor site among children with neuroblastoma, according to study results.Kieuhoa T. Vo
figure Meeting News Coverage

Bone mineral density score disparity highlights need to redefine osteoporosis in children

September 15, 2014
Defining pediatric osteoporosis based on lumbar spine-bone mineral density z score may be problematic due to differences in reference databases and…
In the Journals

Obesity, reduced gonadal function linked in men surviving childhood cancer

August 19, 2014
In boys who have survived cancer, obesity was linked with gonadal dysfunction independent of the effects of treatments previously undergone for the…
figure In the Journals

Noninvasive tool identified high coronary artery disease burden in childhood cancer survivors

August 8, 2014
Coronary CT angiography identified coronary artery disease in a high percentage of adult survivors of childhood Hodgkin’s lymphoma, according…
In the Journals

MRD-directed therapy improved outcomes in pediatric BCR-ABL1–like ALL

August 4, 2014
Pediatric patients with BCR-ABL1–like acute lymphoblastic leukemia who received risk-directed therapy based on minimal residual disease levels…
In the Journals

Antifungal therapy may alter epidemiology of invasive mold infections

August 1, 2014
Treatment with antifungal therapy may be a risk factor for invasive mold infections, according to study findings in The Journal of the Pediatric
Institution Notes

St. Jude announces CEO appointment

HemOnc Today, August 10, 2014
James R. Downing, MD, took over as CEO of St. Jude Children’s Research Hospital in mid-July.
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