Pediatric Oncology

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Gene therapy superior to haploidentical HSCT for SCID-X1

August 26, 2016

Gene therapy was associated with faster T-cell reconstitution and a better long-term thymic output than partially matched hematopoietic stem cell transplantation for children with X-linked severe combined immunodeficiency, according to study results.

“Over the last decade, gene therapy has emerged as a viable alternative to a partial matched stem cell transplant for infants with SCID-X1,” Fabien Touzot, MD, PhD, of the Necker Children’s Hospital in Paris, said in a press release. “To ensure that we are providing the best alternative therapy possible, we wanted to compare outcomes among infants treated with gene therapy and infants receiving partial matched transplants.”

In the Journals Plus

Survivors of Hodgkin lymphoma face high cardiovascular toxicity burden

August 26, 2016
Cardiovascular toxicities occurred more frequently and severely among adult survivors of pediatric, adolescent and young adult Hodgkin lymphoma than in the general…

ASTRO Annual Meeting to reflect theme of ‘enhancing value, improving outcomes’

August 18, 2016
The American Society for Radiation Oncology will hold its annual meeting from Sept. 25 to 28 in Boston. More than 10,000 people are expected to attend, making this one…
In the Journals Plus

Cancer survivors report similar sexual activity, function as others their age

August 17, 2016
Sexual activity and function appeared no different in cancer survivors than in cancer-free adults aged 50 years or older, according to results of a population-based…
CME

The Patient with Multiple Ecchymoses

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Glanzmann’s thrombasthenia is a rare, inherited bleeding disorder that results from a mutation in αIIbß3, an integrin…
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Meeting News Coverage

VIDEO: Merge of immunotherapy, genomics lead to personalized treatment

June 23, 2016
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Discoveries from ASCO 2016: Breast Cancer

Discoveries from ASCO 2016: Breast Cancer

CME

The Patient with Lymphadenopathy

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Castleman’s disease is a rare lymphoproliferative disorder that is characterized by enlargement of 1 (unicentric) or…
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In the Journals

Gene therapy superior to haploidentical HSCT for SCID-X1

August 26, 2016
Gene therapy was associated with faster T-cell reconstitution and a better long-term thymic output than partially matched hematopoietic stem cell…

In the Journals Plus

Survivors of Hodgkin lymphoma face high cardiovascular toxicity burden

August 26, 2016
Cardiovascular toxicities occurred more frequently and severely among adult survivors of pediatric, adolescent and young adult Hodgkin lymphoma than…

ASTRO Annual Meeting to reflect theme of ‘enhancing value, improving outcomes’

August 18, 2016
The American Society for Radiation Oncology will hold its annual meeting from Sept. 25 to 28 in Boston. More than 10,000 people are expected to…

In the Journals Plus

Cancer survivors report similar sexual activity, function as others their age

August 17, 2016
Sexual activity and function appeared no different in cancer survivors than in cancer-free adults aged 50 years or older, according to results of a…

Initiative fuels advancement, access of immuno-oncology in community setting

August 17, 2016
The approval and availability of new immunotherapy treatments sparked the need for dissemination of these therapies to patients throughout the cancer…

In the Journals Plus now live on Healio.com/HemOnc

August 17, 2016
Healio.com/HemOnc has launched In the Journals Plus, a new feature that will provide busy physicians with summaries of the top articles from leading…

Oncofertility experts help physicians, patients understand reproductive consequences of cancer treatment

August 15, 2016
Life-preserving treatments once frequently threatened the fertility of patients with cancer. However, fewer barriers exist today thanks to increasing…

Eight important updates from the FDA

August 12, 2016
The FDA has announced several decisions related to hematology and oncology in the past month. HemOnc Today summarizes eight FDA actions that…

Report: US makes progress with cancer prevention policies, but some states still fall short

August 11, 2016
Progress has been made across the United States to pass and implement legislative solutions to prevent and fight cancer, according to an American…

In the Journals PlusAbstract Only

Does socioeconomic status impact physical activity and sleep among children with cancer?

August 11, 2016
AUTHORS:
Orsey AD, Wakefield DB.

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