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Augmented therapy improves outcomes for children with high-risk Wilms' tumor

May 14, 2015

Augmenting standard therapy with additional agents prolonged EFS for children with favorable histology Wilms’ tumor who had loss of heterozygosity of chromosomes 1p and 16q, according to results of two phase 3 Children’s Oncology Group studies.

Approximately 5% to 6% of children with favorable histology Wilms’ tumor have this chromosomal abnormality, which is associated with a greater risk for relapse, according to study background.

In the Journals

Pediatric cancer treatments increase risk for obesity in adulthood

May 11, 2015
Survivors of pediatric cancers who received cranial radiation or glucocorticoids appeared more likely to be obese later in life, according to study…
Saro H. Armenian, DO In the Journals

Pulmonary defects common among childhood cancer survivors

May 5, 2015
Survivors of pediatric cancers who underwent pulmonary-compromising therapies demonstrated a significant risk for long-term pulmonary complications, according to study…
In the Journals

RAI treatment may increase second primary malignancy risk among children, young adults with thyroid cancer

April 15, 2015
An elevated risk for second primary malignancy, especially salivary gland cancer, was found among pediatric and young adult patients who received radioactive iodine for…
CME
Hematology Oncology Case Consults

Diagnosis and Management of Hemophilia

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of the patient with hemophilia supplemented with a case…
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CME
New Advances, New Options: Evaluating the Changing Landscape of Hemophilia

New Advances, New Options: Evaluating the Changing Landscape of Hemophilia to Optimize Patient Outcomes

This activity is supported by an educational grant from Biogen Idec.

The bleeding abnormalities associated with hemophilia can have devastating consequences for patients. Recent advances…
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Meeting News Coverage

Augmented therapy improves outcomes for children with high-risk Wilms' tumor

May 14, 2015
Augmenting standard therapy with additional agents prolonged EFS for children with favorable histology Wilms’ tumor who had loss of…
In the Journals

Pediatric cancer treatments increase risk for obesity in adulthood

May 11, 2015
Survivors of pediatric cancers who received cranial radiation or glucocorticoids appeared more likely to be obese later in life, according to study…
Saro H. Armenian, DO In the Journals

Pulmonary defects common among childhood cancer survivors

May 5, 2015
Survivors of pediatric cancers who underwent pulmonary-compromising therapies demonstrated a significant risk for long-term pulmonary complications…
In the Journals

RAI treatment may increase second primary malignancy risk among children, young adults with thyroid cancer

April 15, 2015
An elevated risk for second primary malignancy, especially salivary gland cancer, was found among pediatric and young adult patients who received…
In the Journals

GH therapy appears safe in children without risk factors for cancer

April 14, 2015
In children without known risk factors for developing cancer, the use of growth hormone therapy appears to be safe and does not confer an increased…
In the Journals

MRD monitoring may guide risk-based therapy in pediatric ALL

April 10, 2015
The sequential monitoring of minimal residual disease levels during remission induction in pediatric patients with acute lymphoblastic leukemia may…
In the Journals

HSCT outcomes similar in pediatric ALL regardless of donor type

April 6, 2015
 Pediatric patients with high-risk acute lymphoblastic leukemia who underwent hematopoietic stem cell transplantation with matched unrelated…
In the Journals

Morbidity increases among childhood cancer survivors

April 1, 2015
The projected increase in the number of survivors of childhood cancer has corresponded with an increase in the morbidity burden of this population…
In the Journals

Aprepitant effective for CINV prevention in children

March 30, 2015
The addition of aprepitant to ondansetron effectively reduced or prevented chemotherapy-induced nausea and vomiting in pediatric patients who…
In the Journals

Genomic maps could improve pediatric adrenocortical tumor identification, treatment

March 16, 2015
Genomic maps of pediatric adrenocortical tumors have revealed aberrant genetic and chromosomal changes that drive cancer, along with the sequence of…
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