HemOnc Today


The following articles appeared in the print edition of HEMONC TODAY.

Table of Contents

ASH announces award recipients

CMS releases 2015 Quality Measures Report

Cover Story

Expansion of ‘Right to Try’ legislation raises ethical, safety concerns


Pancreatic cancer: Great expectations or false promises

Derek Raghavan, MD, PhD

FDA News

FDA grants orphan drug designation to sevuparin for sickle cell disease

FDA grants orphan drug designation to AG-348 for pyruvate kinase deficiency

FDA grants marketing authorization for direct-to-consumer genetic test for Bloom syndrome

FDA grants priority review for expanded use of Kyprolis in relapsed multiple myeloma

FDA issues final guidance on medical device data systems

In Practice

State of the science: High-priority transplant trials for nonmalignant disease

Hemant Murthy, MD; William Wood, MD

In the Journals

MRI improved mammography screening sensitivity for older BRCA mutation carriers

Most benign thyroid nodules remain benign during follow-up

MRI shows greater screening sensitivity for familial breast cancer

Ibrutinib discontinuation linked to poor prognosis in CLL

Oncologists examine rising costs of cancer drugs

Lenalidomide combination fails to improve survival in castration-resistant prostate cancer

Low testosterone predicts improved outcomes with continuous ADT in prostate cancer

Low-dose iron supplementation improves hemoglobin recovery after blood donation

Informed choice for breast cancer screening may result in fewer mammograms

Model predicts bloodstream infection risk in febrile pediatric cancer patients

The Challenge of Submassive Pulmonary Embolism

Time-dependent treatment may lead to better CML outcomes

Smoking increases mortality risk in patients with colorectal cancer

Testosterone therapy did not increase prostate cancer risk in hypogonadal men

Waldenström’s macroglobulinemia increases risk for secondary malignancies

Wide excision, Mohs micrographic surgery effectively treated primary lentigo maligna

Two-thirds of patients with invasive cancer likely to survive 5 years

Variation in risk for late mortality among pediatric cancer survivors can persist up to 20 years post-diagnosis

Prostate cancer diagnosis in first-degree relative increases woman's risk for breast cancer

Reconstruction for pelvic tumors achieves satisfactory survival, increases complication rates

Parents interested in whole genome sequencing for themselves, children

Prior MGUS diagnosis increases multiple myeloma survival

Scent-trained canine detects thyroid cancer in urine samples, could aid in diagnoses

Smoking, alcohol may increase gastrostomy duration in head and neck cancers

Reporting of noninferiority trial results needs improvement

Safety policies, data protection needed for BYOD in health care

Cancer prevalence low in women who undergo myomectomy with electric power morcellation

Cancer fear limits colorectal cancer screening uptake

Breast cancer screening program highlights health care disparities

Defibrotide represents ‘major advance’ for severe veno-occlusive disease after HSCT

Combination of trastuzumab, XELOX shows promise for advanced gastric cancer

Chest CT imaging may safely be omitted from neuroblastoma surveillance for pediatric patients

Addition of ibrutinib to chemoimmunotherapy shows promise for CLL

Active surveillance may be appropriate for favorable intermediate-risk prostate cancer

80% adherence to colorectal cancer screening could prevent 200,000 deaths by 2030

Bortezomib-based therapy improves outcomes, increases toxicity in mantle cell lymphoma

Blood transfusions during CABG increased risk for pneumonia

Adjuvant radiotherapy may benefit patients with lymph node-positive vulvar cancer

Despite clinical success, laparoscopic colectomy underused in colon cancer treatment

HSCT outcomes similar in pediatric ALL regardless of donor type

Extra-virgin olive oil ingredient rapidly induces cancer cell death

Four-factor prothrombin complex concentrate shows promise for urgent vitamin K antagonist reversal

Fondaparinux found to be effective in prevention of thrombotic events in patients with HIT

DNA from breast cancer tumors could lead to genotype misclassification

Early alopecia linked to favorable outcomes in epithelial ovarian cancer

Despite fewer smokers, poor screening criteria may raise lung cancer mortality

Institution Notes

ASCO to honor several researchers

St. Jude appoints chair of radiation

AACR presents achievement award

AACR announces president-elect

MD Anderson names division head

Lymphoma expert joins City of Hope

Weill Cornell names chair of radiation

Meeting News Coverage

Extent of spinal metastasis should drive patient-centered management of MESCC

HIV did not affect HCC recurrence or survival after LT

MM-398 improved outcomes in metastatic pancreatic cancer

Algorithm to test microRNA on fine needle aspiration could improve molecular cytology diagnostic yield

Thyroid cancer risk greater in survivors of breast cancer