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Chest CT imaging may safely be omitted from neuroblastoma surveillance for pediatric patients

February 27, 2015

Neuroblastoma progression or recurrence in the chest is rare among children and usually can be detected with non-CT imaging modalities or through the presentation of symptoms, according to study results.

The findings suggest chest CT imaging may safely be omitted from neuroblastoma surveillance, allowing for a 35% to 42% reduction in radiation burden among these patients, results showed.

FDA NewsDrug Pipeline

FDA grants breakthrough therapy designation to Rintega for EGFRvIII-positive glioblastoma

February 23, 2015
 The FDA today granted breakthrough therapy designation to rindopepimut for the treatment of adults with epidermal growth factor receptor variant III-positive…
FDA NewsDrug Pipeline

FDA grants orphan drug status to BXQ-350 for treatment of glioblastoma multiforme

February 16, 2015
The FDA granted orphan drug designation to BXQ-350, an agent in development for treatment of glioblastoma multiforme.BXQ-350 (Bexion Pharmaceuticals) is a proprietary…
Meeting News CoveragePerspective

Optune plus temozolomide extended survival in glioblastoma

February 6, 2015
Use of the noninvasive regional therapy Optune with temozolomide chemotherapy significantly extended OS and PFS in patients with newly diagnosed glioblastoma, according…
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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates - Monograph

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In the Journals

Chest CT imaging may safely be omitted from neuroblastoma surveillance for pediatric patients

February 27, 2015
Neuroblastoma progression or recurrence in the chest is rare among children and usually can be detected with non-CT imaging modalities or through the…
FDA NewsDrug Pipeline

FDA grants breakthrough therapy designation to Rintega for EGFRvIII-positive glioblastoma

February 23, 2015
 The FDA today granted breakthrough therapy designation to rindopepimut for the treatment of adults with epidermal growth factor receptor…
FDA NewsDrug Pipeline

FDA grants orphan drug status to BXQ-350 for treatment of glioblastoma multiforme

February 16, 2015
The FDA granted orphan drug designation to BXQ-350, an agent in development for treatment of glioblastoma multiforme.BXQ-350 (Bexion Pharmaceuticals)…
Meeting News CoveragePerspective

Optune plus temozolomide extended survival in glioblastoma

February 6, 2015
Use of the noninvasive regional therapy Optune with temozolomide chemotherapy significantly extended OS and PFS in patients with newly diagnosed…
FDA NewsDrug Pipeline

FDA grants orphan drug status to SL-701 for glioma treatment

January 30, 2015
The FDA today granted orphan drug designation to SL-701 for the treatment of glioma, according to a press release from the drug’s…
In the Journals

Bevacizumab-induced hypertension associated with improved OS, PFS in glioblastoma

January 27, 2015
Patients with recurrent glioblastoma who experienced bevacizumab-induced hypertension demonstrated prolonged OS and PFS, according to study…
Kate Nathanson In the Journals

ATRX mutation possible biomarker for rare neuroendocrine tumors

January 22, 2015
A somatic mutation in the ATP-dependent helicase, or ATRX,  gene — recently demonstrating potential as a molecular marker for…
In the Journals

IG-IMRT showed favorable outcomes in skull base chordoma, chondrosarcoma

January 19, 2015
Patients with chordomas or chondrosarcomas of the skull base had favorable 5-year OS and local control after high-dose image-guided…
FDA News

FDA grants orphan drug, rare pediatric disease status to entrectinib for neuroblastoma

December 29, 2014
The FDA has granted both orphan drug designation and rare pediatric disease designation to entrectinib for the treatment of neuroblastoma, according…
In the Journals

Sunitinib appeared active in meningioma

December 23, 2014
Sunitinib appeared effective in patients with recurrent atypical and malignant meningioma, according to results of a prospective, multicenter, phase…
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