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Genomic data may better classify lower-grade glioma than histology

June 30, 2015

Read the Perspective from Stephanie Weiss, MD, MD

IDH, 1p/19q and TP53 status more accurately represented three molecular classes of lower-grade gliomas than histologic class, according to study results.

Lower-grade gliomas with an IDH mutation also had codeletion of chromosome arms 1p and 19q or a TP53 mutation, whereas lower-grade gliomas without IDH mutations demonstrated molecular and clinical similarity to glioblastoma, results showed.

Paula T. Rieger RN, MSN, CAE, FAAN Meeting HighlightsPublication Exclusive

Oncology nurses showcase ‘passion for excellence’ at 40th ONS Congress

HemOnc Today, June 25, 2015
Paula T. Rieger, RN, MSN, CAE, FAAN
The Oncology Nursing Society 40th Annual Congress brought together more than 3,000 nurses with a passion for excellence in the care they provide, as well as a desire to…
In the Journals

Promoter mutations redefine molecular subgroups of gliomas

June 17, 2015
Gliomas can be classified into five distinct categories based on the presence of IDH, 1p/19q codeletion and TERT promoter mutations, according to study results.These…
In the Journals

Anticoagulants safe for patients with brain metastases

June 9, 2015
The use of anticoagulant medication did not increase the risk for intracranial hemorrhage among cancer patients with brain metastases, according to the results of a…
CME CNE
High Risk AAMDS

Treatment Decision-Making through the Spectrum of MDS:
Case 2 High Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
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CME
Hematology Oncology Case Consults

Diagnosis and Management of Hemophilia

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of the patient with hemophilia supplemented with a case…
More »
In the JournalsPerspective

Genomic data may better classify lower-grade glioma than histology

June 30, 2015
IDH, 1p/19q and TP53 status more accurately represented three molecular classes of lower-grade gliomas than histologic class, according to study…
Paula T. Rieger RN, MSN, CAE, FAAN Meeting HighlightsPublication Exclusive

Oncology nurses showcase ‘passion for excellence’ at 40th ONS Congress

HemOnc Today, June 25, 2015
Paula T. Rieger, RN, MSN, CAE, FAAN
The Oncology Nursing Society 40th Annual Congress brought together more than 3,000 nurses with a passion for excellence in the care they provide, as…
In the Journals

Promoter mutations redefine molecular subgroups of gliomas

June 17, 2015
Gliomas can be classified into five distinct categories based on the presence of IDH, 1p/19q codeletion and TERT promoter mutations, according to…
In the Journals

Anticoagulants safe for patients with brain metastases

June 9, 2015
The use of anticoagulant medication did not increase the risk for intracranial hemorrhage among cancer patients with brain metastases, according to…
Meeting News CoveragePerspective

Risks of adjuvant WBRT may outweigh benefits for limited brain metastases

June 2, 2015
CHICAGO — Whole-brain radiation therapy after stereotactic radiosurgery controlled brain metastases but did not improve OS in patients with one…
Drug PipelinePerspectivePublication Exclusive

2015 Oncology Drugs in the Pipeline

HemOnc Today, May 25, 2015
HemOnc Today’s annual Oncology Drugs in the Pipeline chart lists agents in phase 2 or phase 3 development for a variety of indications. Clinicians…
In the Journals

Combined surgical diagnostic tools improve gross total resection, not survival, in glioma

May 21, 2015
Intraoperative MRI and 5-aminolevulinic acid were not predictors of improved survival in patients with glioma when used together, according to data…
Stephen R. Rapp, PhD In the Journals

Donepezil displays some cognitive benefit for patients with irradiated brain tumors

May 13, 2015
Donepezil was not associated with significant improvements in cognitive functioning among survivors of brain tumors who underwent irradiation…
In the JournalsPerspective

Some long-term survivors of low-grade glioma experience decline in health-related quality of life

May 7, 2015
Some long-term survivors of low-grade glioma may experience a significant decline in physical role function and general health perceptions despite…
FDA News

FDA grants orphan drug designation to Reolysin for malignant gliomas

April 17, 2015
The FDA today granted orphan drug designation to pelareorep for the treatment of patients with malignant gliomas, according to a press release from…
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