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Intracardiac thrombi rates lower with dabigatran, rivaroxaban, compared with phenprocoumon

March 6, 2015

The prevalence of intracardiac thrombi was lower in high-risk patients with atrial fibrillation and flutter treated with direct oral anticoagulants compared with phenprocoumon, according to German researchers.

“This result is in line with clinical efficacy of direct oral anticoagulants for the prevention of [thromboembolism],” Maura M. Zylla, MD, and colleagues wrote in their study, published in the American Journal of Cardiology.

Study: No benefit from anticoagulant use in Behçet’s disease

March 3, 2015
Patients with vascular manifestations of Behçet’s disease who received treatment with anticoagulants did not benefit from the therapy given in addition to…
Suzanne C. Cannegieter, MD, PhD In the Journals

Data support predictive significance of superficial vein thrombosis

March 2, 2015
Researchers found that a history of superficial vein thrombosis may be predictive of venous and arterial thrombotic events and these findings may play an important role…

Boehringer Ingelheim files BLA for antidote to dabigatran

March 2, 2015
Boehringer Ingelheim announced that it has submitted a biologics license application to the FDA requesting an accelerated approval pathway for idarucizumab, an antidote…
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Treatment Decision-Making through the Spectrum of MDS:
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An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
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Lowering Factor XI levels effective in prevention of venous thrombosis

Lowering Factor XI levels effective in prevention of venous thrombosis

December 11, 2014
SAN FRANCISCO – A late-breaking abstract presented at the ASH Annual Meeting and Exposition identified a novel…
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Hot melanoma

Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates - Monograph

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
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Maura M. Zylla, MD In the Journals

Intracardiac thrombi rates lower with dabigatran, rivaroxaban, compared with phenprocoumon

March 6, 2015
The prevalence of intracardiac thrombi was lower in high-risk patients with atrial fibrillation and flutter treated with direct oral anticoagulants…

Study: No benefit from anticoagulant use in Behçet’s disease

March 3, 2015
Patients with vascular manifestations of Behçet’s disease who received treatment with anticoagulants did not benefit from the therapy…
Suzanne C. Cannegieter, MD, PhD In the Journals

Data support predictive significance of superficial vein thrombosis

March 2, 2015
Researchers found that a history of superficial vein thrombosis may be predictive of venous and arterial thrombotic events and these findings may…

Boehringer Ingelheim files BLA for antidote to dabigatran

March 2, 2015
Boehringer Ingelheim announced that it has submitted a biologics license application to the FDA requesting an accelerated approval pathway for…
FDA NewsDrug Pipeline

FDA grants orphan drug status to Factor Xa inhibitor antidote

February 26, 2015
The FDA has granted orphan drug designation to andexanet alfa for the treatment of patients with serious, uncontrolled bleeding events or who require…
Alejandro Lazo-Langner, MD, MSc In the Journals

Fondaparinux found to be effective in prevention of thrombotic events in patients with HIT

February 26, 2015
Non-heparin anticoagulant fondaparinux was found to be as effective and had a similar safety profile compared with other non-heparin anticoagulants…
In the Journals

Researchers identify approaches to manage anticoagulant-related intracerebral hemorrhage

February 24, 2015
Attainment of two clearly defined clinical thresholds — one related to international normalized ratio reversal and the other related to…
John B. Holcomb, MD In the Journals

Military protocol may benefit civilians in need of massive blood transfusion

February 20, 2015
Damage control resuscitation, an emergency procedure used in the military to try to save the lives of injured personnel with massive blood loss, may…
In the Journals

Odds of major bleeding, mortality lower with fondaparinux than heparin

February 19, 2015
Patients with non-STEMI who were treated with fondaparinux had better rates of major bleeding and mortality during hospitalization and up to 180 days…
In the Journals

Donor leukocyte telomere length linked to transplantation outcomes in aplastic anemia

February 10, 2015
Longer donor leukocyte telomere length was associated with improved survival in patients with severe aplastic anemia who underwent allogeneic…
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