Hematology

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Common antibiotic may decrease anticoagulant effect of warfarin

August 27, 2015

Treatment with the antibiotic dicloxacillin significantly decreased international normalized ratio levels among patients taking vitamin K antagonists, according to the results of a registry-based study.

The use of vitamin K antagonists (VKAs) pose a potential risk for drug–drug interactions, resulting in insufficient or excessive anticoagulation; however, most alleged interactions lacked solid data. Previous reports suggested that dicloxacillin — a commonly used antibiotic — lowered the anticoagulant effect of warfarin.

In the Journals

Acute kidney injury, electrolyte abnormalities common among Ebola cases

August 25, 2015
Recently published data from an Ebola treatment center revealed a high prevalence of hematological and biochemical abnormalities among patients with at least a mild case…
FDA News

FDA expands approval of Promacta for pediatric patients with ITP

August 24, 2015
The FDA today expanded the approval of eltrombopag for children aged 1 year or older with chronic immune thrombocytopenia who experienced an insufficient response to…
David A. Williams, MD Institution Notes

ASH presents bridge grants to 13 investigators

August 22, 2015
Thirteen investigators received ASH bridge grants in August.The 1-year, $150,000 awards are intended to provide interim support for promising hematology research…
CME
Hematology Oncology Case Consults

Diagnosis and Management of Hemophilia

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of the patient with hemophilia supplemented with a case…
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Meeting News Coverage Video
Genome editing demonstrated wide application for blood disorders

Genome editing demonstrated wide application for blood disorders

January 5, 2015
SAN FRANCISCO — Ralph Green, MD, PhD, FRCPath, medical director of the UC Davis Health System Medical…
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In the Journals

Common antibiotic may decrease anticoagulant effect of warfarin

August 27, 2015
Treatment with the antibiotic dicloxacillin significantly decreased international normalized ratio levels among patients taking vitamin K…
In the Journals

Acute kidney injury, electrolyte abnormalities common among Ebola cases

August 25, 2015
Recently published data from an Ebola treatment center revealed a high prevalence of hematological and biochemical abnormalities among patients with…
FDA News

FDA expands approval of Promacta for pediatric patients with ITP

August 24, 2015
The FDA today expanded the approval of eltrombopag for children aged 1 year or older with chronic immune thrombocytopenia who experienced an…
David A. Williams, MD Institution Notes

ASH presents bridge grants to 13 investigators

August 22, 2015
Thirteen investigators received ASH bridge grants in August.The 1-year, $150,000 awards are intended to provide interim support for promising…

PCORI grants millions in funding for 'pragmatic clinical' research

August 19, 2015
The Patient-Centered Outcomes Research Institute Board of Governors has approved $65.7 million in funding for research studies, along with offering…
In the Journals

VTE risk assessment model validated for critically ill surgical patients

August 19, 2015
The Caprini venous thromboembolism risk assessment model is valid and can be used to determine the potential for venous thromboembolism in patients…
Breaking News

OMS721 demonstrates activity in thrombotic microangiopathies

August 18, 2015
The human monoclonal antibody OMS721 appeared effective for the treatment of patients with thrombotic microangiopathies, according to results of a…
Agnes Y.Y. Lee, MD, MSc In the Journals

Tinzaparin fails to significantly reduce recurrent VTE compared with warfarin

August 18, 2015
The use of daily tinzaparin for 6 months did not significantly reduce recurrent venous thromboembolism, major bleeding or death compared with…
In the Journals

Financial penalties for hospital-acquired VTE do not account for unpreventable incidents

August 17, 2015
Imposing financial penalties based solely on the total number of patients who experience venous thromboembolism failed to account for incidents that…
In the Journals

HLA biomarker may predict GVHD risk following HSCT

August 12, 2015
The HLA-DPB1 rs9277534 expression marker influenced the risk for graft-versus-host disease associated with HLA-DPB1 mismatching, according to study…
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