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Lexaptepid shows promise for anemia of inflammation treatment

September 9, 2014

The experimental drug lexaptepid achieved clinically relevant results in inhibiting the hepcidin production involved in anemia of inflammation, according to recent findings.

Moreover, hepcidin does not appear to disrupt the immune response to inflammation.

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The changing face of our major meetings: Evolution or revolution?

HemOnc Today, September 10, 2014
John Sweetenham, MD, PhD
One morning in late July, I was poised over my laptop at exactly 9 a.m. Mountain time, ready for the ASH Annual Meeting and Exposition registration and housing website…
figure In the JournalsPerspective

HLA-matched donors available for most HSCT candidates

HemOnc Today, September 10, 2014
A majority of hematopoietic stem-cell transplantation candidates who do not have related donors have suitable adult donors or cord-blood units through the National…
figure In the Journals

Anemia treatment not beneficial after brain injury

August 27, 2014
Two frequently used anemia treatments did not improve short-term neurocognitive outcomes in patients who experienced a traumatic brain injury, according to results of a…
CME
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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates

This activity is supported by an educational grant from Merck & Co., Inc.

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
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CME CNE
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Treatment Decision-Making through the Spectrum of MDS: Case 1 Low Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain MDS…
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In the Journals

Lexaptepid shows promise for anemia of inflammation treatment

September 9, 2014
The experimental drug lexaptepid achieved clinically relevant results in inhibiting the hepcidin production involved in anemia of inflammation…
figure Editorial Publication Exclusive

The changing face of our major meetings: Evolution or revolution?

HemOnc Today, September 10, 2014
John Sweetenham, MD, PhD
One morning in late July, I was poised over my laptop at exactly 9 a.m. Mountain time, ready for the ASH Annual Meeting and Exposition registration…
figure In the Journals Perspective

HLA-matched donors available for most HSCT candidates

HemOnc Today, September 10, 2014
A majority of hematopoietic stem-cell transplantation candidates who do not have related donors have suitable adult donors or cord-blood units…
figure In the Journals

Anemia treatment not beneficial after brain injury

August 27, 2014
Two frequently used anemia treatments did not improve short-term neurocognitive outcomes in patients who experienced a traumatic brain injury…
FDA approvals

FDA expands approval of Promacta

August 26, 2014
The FDA today expanded the improved indications for eltrombopag to include treatment of patients with severe aplastic anemia who demonstrated an…
figure In the Journals

Aspirin reduced risk for recurrent VTE

August 25, 2014
Aspirin after anticoagulation reduced the risk for recurrent venous thromboembolism by more than one-third in patients with a first unprovoked VTE…
FDA approvals

FDA approves Eliquis for treatment of DVT, PE

August 21, 2014
The FDA has approved a supplemental new drug application for apixaban, an oral selective Factor Xa inhibitor, for the treatment of deep vein…
figure In the Journals

Regular transfusions reduced stroke recurrence in pediatric sickle cell anemia

August 20, 2014
Children with sickle cell anemia who underwent regular blood-transfusion therapy experienced fewer recurrences of cerebral infarct, according to…
In the Journals Perspective

Newborn screening identified higher incidence of SCID

August 19, 2014
Newborn screening for severe combined immunodeficiency detected the condition in 1 out of every 58,000 births.This population-based rate was higher…
In the Journals

Adolescents, young adults with sickle cell disease have higher rates of chlamydia

August 19, 2014
Adolescents and young adults with sickle cell disease are more likely to have asymptomatic chlamydia compared with adolescents without the disease…
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