Head/Neck Cancer

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Persistent HPV16 DNA in oral rinses predicts oropharyngeal cancer recurrence

July 31, 2015

Read the Perspective from Miriam N. Lango, MD

The presence of HPV type 16 DNA in oral rinses following treatment for HPV-related oropharyngeal cancer corresponded with poor prognosis and may serve as a potential biomarker for long-term tumor surveillance and local recurrence, according to results of a prospective cohort study.

The incidence of HPV-related oropharyngeal carcinoma (HPV-OPC) has increased in the U.S. and despite its favorable prognosis, recurrence occurs in 10% to 25% of cases. Gypsyamber D’Souza, PhD, MS, associate professor of cancer epidemiology at Johns Hopkins Bloomberg School of Public Health, and colleagues sought to determine whether HPV DNA detection in oral rinses following treatment for HPV-OPC served as a prognostic biomarker for recurrence and survival.

Top Takeaways from ASCO: HPV-associated head and neck cancer Meeting News Coverage

Top Takeaways from ASCO: HPV-associated head and neck cancer

July 30, 2015
CHICAGO — De-intensified chemoradiation was efficacious in patients with low-risk, HPV-associated oropharyngeal squamous cell carcinoma, according to findings…
David J. Adelstein, MD, FACP Meeting News Coverage

Top Takeaways from ASCO: Therapeutic dosing in head and neck cancer

July 30, 2015
CHICAGO — Cisplatin administered in a low-dose, weekly regimen may not be equivalent to standard high-dose, intermittent cisplatin in locally advanced head and…
Charis Eng, MD, PhD In the Journals

Risk calculator an accurate, cost-effective prescreening tool for PTEN mutations

July 30, 2015
The PTEN Cleveland Clinic score appeared to be a cost-effective prescreening tool to identify patients with Cowden-like disease who are appropriate candidates for…
Tailored Therapies for Myelodysplastic Syndromes

Tailored Therapies for Myelodysplastic Syndromes

This activity is supported by an educational grant from Celgene Corporation.

Myelodysplastic syndromes (MDS) represent a group of myeloid clonal hemopathies with heterogeneous clinical…
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Meeting News Coverage Video
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VIDEO: Ethical issues arise in genetic screening of thyroid cancer

March 7, 2015
SAN DIEGO — In this video exclusive, M. Sara Rosenthal, MD, director of the program for bioethics at the…
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CME
Immunotherapy Updates 2015: FOCUS on NSCLC

Immunotherapy Updates 2015: FOCUS on NSCLC

This activity is supported by educational grants from Genentech, Inc. and Merck & Co., Inc.

Globally, lung cancer is the leading cause of cancer-related deaths. Non-small cell lung cancer (NSCLC) accounts for…
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Perspective

Persistent HPV16 DNA in oral rinses predicts oropharyngeal cancer recurrence

July 31, 2015
The presence of HPV type 16 DNA in oral rinses following treatment for HPV-related oropharyngeal cancer corresponded with poor prognosis and may…
Top Takeaways from ASCO: HPV-associated head and neck cancer Meeting News Coverage

Top Takeaways from ASCO: HPV-associated head and neck cancer

July 30, 2015
CHICAGO — De-intensified chemoradiation was efficacious in patients with low-risk, HPV-associated oropharyngeal squamous cell carcinoma…
David J. Adelstein, MD, FACP Meeting News Coverage

Top Takeaways from ASCO: Therapeutic dosing in head and neck cancer

July 30, 2015
CHICAGO — Cisplatin administered in a low-dose, weekly regimen may not be equivalent to standard high-dose, intermittent cisplatin in locally…
Charis Eng, MD, PhD In the Journals

Risk calculator an accurate, cost-effective prescreening tool for PTEN mutations

July 30, 2015
The PTEN Cleveland Clinic score appeared to be a cost-effective prescreening tool to identify patients with Cowden-like disease who are appropriate…
SupplementPublication Exclusive

Perspectives from ASCO 2015: A HemOnc Today Special Report

HemOnc Today, July 25, 2015
This year’s ASCO Annual Meeting featured the theme “Illumination and Innovation: Transforming Data into Learning.”As such, meeting…
Top Takeaways from ASCO: Advanced squamous cell carcinoma of the head and neck Meeting News Coverage

Top Takeaways from ASCO: Advanced squamous cell carcinoma of the head and neck

July 23, 2015
Data from two high-profile trials presented at the ASCO Annual Meeting assessed treatment options and quality of life for patients with advanced head…
In the JournalsPerspective

Epstein-Barr virus DNA may predict treatment efficacy for advanced nasopharyngeal cancer

July 21, 2015
Plasma Epstein-Barr virus DNA may serve as the most significant prognostic biomarker for adjuvant therapy selection in patients with nasopharyngeal…
In the Journals

Total laryngectomy may be underused in advanced larynx cancer

July 20, 2015
A majority of patients with T4a larynx cancer received larynx preservation chemoradiation rather than the guideline-recommended total laryngectomy…
Jeffrey Bumpous, MD Institution Notes

University selects chair for newly created otolaryngology department

July 11, 2015
Jeffrey Bumpous, MD, has been named chair of the University of Louisville’s newly created department of otolaryngology — head and neck…
In the Journals

Cervical lymph node metastases compromise survival of younger patients with thyroid cancer

July 10, 2015
The presence of cervical lymph node metastases appeared to worsen survival in younger patients with papillary thyroid cancer, according to study…
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