Gynecologic Cancer

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PD-L1 expression may predict immunotherapy response in cervical, vulvar squamous cell carcinoma

May 25, 2016

Recurrent copy number gains to the genes that encode the PD-1 ligands appeared associated with PD-L1 expression in certain patients with cervical and vulvar squamous cell carcinoma, according to a genetic analysis.

These genetic expressions could help identify patients who may benefit from therapies targeting programmed cell death protein 1 (PD-1), according to the researchers.

Cover Story

Value in cancer care must ‘start with patients, not dollars’

HemOnc Today, May 25, 2016
The skyrocketing cost of cancer care has come under intense criticism from patients and health care providers.Several promising treatments — including traditional…
In the JournalsPerspective

Refocusing public narrative necessary to raise ‘alarmingly low’ HPV vaccination rates

HemOnc Today, May 25, 2016
Greater uptake of HPV vaccination should be a priority to reduce the worldwide cancer burden, according to an ASCO policy statement.The statement aims to increase…
In the JournalsPerspective

HIV patients less likely to receive treatment for many cancers

May 23, 2016
An analysis of more than 2 million U.S. cancer patients suggested that those with HIV are less likely to receive cancer treatment, regardless of insurance status or…
CME

The Patient with Multiple Ecchymoses

No commercial support for this activity.

Glanzmann’s thrombasthenia is a rare, inherited bleeding disorder that results from a mutation in αIIbß3, an integrin…
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Meeting News Coverage

Expert highlights advances in targeted therapies for gynecologic cancers

June 10, 2014
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AACR Annual Meeting

AACR Annual Meeting

CME

The Patient with Severe Leukocytosis

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Currently five tyrosine kinase inhibitors are available for use in patients with chronic myeloid leukemia (CML)…
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In the Journals

PD-L1 expression may predict immunotherapy response in cervical, vulvar squamous cell carcinoma

May 25, 2016
Recurrent copy number gains to the genes that encode the PD-1 ligands appeared associated with PD-L1 expression in certain patients with cervical and…

Cover Story

Value in cancer care must ‘start with patients, not dollars’

HemOnc Today, May 25, 2016
The skyrocketing cost of cancer care has come under intense criticism from patients and health care providers.Several promising treatments —…

In the JournalsPerspective

Refocusing public narrative necessary to raise ‘alarmingly low’ HPV vaccination rates

HemOnc Today, May 25, 2016
Greater uptake of HPV vaccination should be a priority to reduce the worldwide cancer burden, according to an ASCO policy statement.The statement…

In the JournalsPerspective

HIV patients less likely to receive treatment for many cancers

May 23, 2016
An analysis of more than 2 million U.S. cancer patients suggested that those with HIV are less likely to receive cancer treatment, regardless of…

‘Surge’ in unnecessary CT scans significantly increases cancer risks

May 23, 2016
A single standard CT scan may increase the risk for fatal cancer in one of every 2,000 patients, according to FDA data.Repeat or excessive exposure…

In the JournalsPerspective

Lifestyle changes can reduce cancer incidence, mortality

May 20, 2016
The adoption of healthy lifestyle practices may prevent a large proportion of cancers and reduce cancer mortality in the United States, according to…

Meeting News CoveragePerspective

Precision medicine approach improves outcomes in phase 1 trials

May 19, 2016
Patients treated in phase 1 trials designed with a biomarker-based approach for treatment selection demonstrated higher response rates and longer…

Six recent studies highlight continued disparities in cancer care

May 18, 2016
Despite significant advances in cancer prevention, screening and treatment, considerable disparities remain.These disparities can be based on several…

Congressional subcommittee debates Medicare Part B demonstration project

May 17, 2016
The U.S. House Energy Subcommittee on Health today held a hearing to offer doctor and patient perspectives on planned changes to the Medicare Part B…

In the Journals

Volasertib demonstrates antitumor activity without PFS benefit in ovarian cancer

May 16, 2016
Although volasertib demonstrated antitumor activity in patients with platinum-resistant or platinum-refractory ovarian cancer, it failed to extend…

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