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FOLFOXIRI plus bevacizumab improved outcomes, increased toxicity in metastatic colorectal cancer

October 22, 2014

Patients with metastatic colorectal cancer who received first-line treatment with bevacizumab plus FOLFOXIRI chemotherapy demonstrated significantly longer PFS than those treated with bevacizumab plus FOLFIRI chemotherapy, according to results of a randomized phase 3 study.

However, bevacizumab plus FOLFOXIRI was associated with higher rates of certain adverse events, results showed.

In the Journals

Risk-adjusted model reveals little variation in hospital readmissions after colorectal cancer surgery

October 22, 2014
Researchers who used a risk-adjusted model to evaluate readmission rates after colorectal cancer surgery found little variation between hospitals.The finding raises…
Meeting News Coverage

Incidence of small bowel tumors increased over the last decade

October 22, 2014
PHILADELPHIA — Small bowel tumor incidence rates have increased over the last decade among various ethnic groups, according to data presented at the ACG Annual…
Meeting News Coverage

Advanced histology in diminutive adenomas three-fold higher in CRC vs. screening patients

October 22, 2014
PHILADELPHIA — Advanced histology in lesions sized 9 mm or less occurred at a higher rate in patients with colorectal cancer compared with patients who underwent…
CME
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Targeted Therapy and Immunotherapy in the Management of Metastatic Melanoma: 2014 Updates - Monograph

Melanoma remains a challenging condition for clinicians. An array of targeted therapies and immunotherapy are in…
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CME CNE
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Treatment Decision-Making through the Spectrum of MDS: Case 1 Low Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain MDS…
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In the Journals

FOLFOXIRI plus bevacizumab improved outcomes, increased toxicity in metastatic colorectal cancer

October 22, 2014
Patients with metastatic colorectal cancer who received first-line treatment with bevacizumab plus FOLFOXIRI chemotherapy demonstrated significantly…
In the Journals

Risk-adjusted model reveals little variation in hospital readmissions after colorectal cancer surgery

October 22, 2014
Researchers who used a risk-adjusted model to evaluate readmission rates after colorectal cancer surgery found little variation between hospitals.The…
Meeting News Coverage

Incidence of small bowel tumors increased over the last decade

October 22, 2014
PHILADELPHIA — Small bowel tumor incidence rates have increased over the last decade among various ethnic groups, according to data presented…
Meeting News Coverage

Advanced histology in diminutive adenomas three-fold higher in CRC vs. screening patients

October 22, 2014
PHILADELPHIA — Advanced histology in lesions sized 9 mm or less occurred at a higher rate in patients with colorectal cancer compared with…
figure Meeting News Coverage

Celecoxib prevented colorectal polyps in children with familial adenomatous polyposis

October 21, 2014
PHILADELPHIA — Celecoxib reduced event rate and delayed progression of adenomas in children with familial adenomatous polyposis, known as FAP…
figure Meeting News Coverage Perspective

Repeat exam of right colon with retroflexed, forward views achieved comparable adenoma detection

October 21, 2014
PHILADELPHIA — Adenoma detection rates in patients undergoing colonoscopy for colorectal cancer screening were similarly improved with a second…
figure In the Journals

Knowledge of individual risk did not increase colorectal cancer screening adherence

October 20, 2014
Receipt of individualized genetic and environmental risk assessments did not increase colorectal cancer screening rates, even among study…
FDA News

FDA grants fast track designation to TAS-102 for mCRC

October 20, 2014
The FDA granted fast track designation to an investigational drug combination as a potential treatment for patients with refractory metastatic…
In the Journals

Men at fourfold higher risk for esophageal adenocarcinoma

October 17, 2014
Men, particularly those with adenocarcinoma, have a significantly higher risk for developing esophageal cancer compared with women worldwide, with a…
In the Journals

Medicare reimbursement policy failed to significantly reduce chemotherapy cost

October 16, 2014
The Medicare Prescription Drug, Improvement and Modernization Act of 2003, intended to slow the skyrocketing costs of drugs the federal government…
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