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LT patients with cirrhosis had increased risk for colorectal neoplasia

September 2, 2014

Patients with viral or alcohol-related cirrhosis awaiting liver transplantation and who underwent colonoscopy were at high risk for developing colorectal neoplasia, according to new study data.

Researchers analyzed data from colonoscopy screenings of two cohorts of 1,134 adult patients awaiting liver transplantation to determine if cirrhosis was a risk factor for colorectal neoplasia. One group consisted of patients with cirrhosis (n=567) and the other was a control group matched for BMI, age, sex, smoking and diabetes (n=567). Each group was 72.3% men; median age was 54 years.

Steady $7.7 billion market projected for colorectal cancer therapy through 2023

September 2, 2014
The colorectal cancer therapeutics market will remain steady at approximately $7.7 billion by 2023 in the US, France, Germany, Italy, Spain, the United Kingdom and…
figure In the Journals

Hispanic veterans with HCV at higher risk for cirrhosis, HCC

September 1, 2014
Hispanic veterans with hepatitis C virus infection had a higher risk for developing cirrhosis or hepatocellular carcinoma compared with African-American and non-Hispanic…
FDA News

FDA lifts clinical hold on vantictumab for NSCLC, breast cancer, pancreatic cancer

August 31, 2014
OncoMed Pharmaceuticals recently announced that the FDA has removed the partial clinical hold on enrollment in phase 1 clinical trials for the company’s monoclonal…
CME

Applying Imaging, Biomarkers, and Immunotherapy in the Management of NSCLC

This activity is supported by an educational grant from Genentech, Inc.

8/7/2014
Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, but the numerous subtypes make this disease…
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CME CNE

Treatment Decision-Making through the Spectrum of MDS: Case 1 Low Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

8/20/2014
MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain MDS…
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In the Journals

LT patients with cirrhosis had increased risk for colorectal neoplasia

September 2, 2014
Patients with viral or alcohol-related cirrhosis awaiting liver transplantation and who underwent colonoscopy were at high risk for developing…

Steady $7.7 billion market projected for colorectal cancer therapy through 2023

September 2, 2014
The colorectal cancer therapeutics market will remain steady at approximately $7.7 billion by 2023 in the US, France, Germany, Italy, Spain, the…
figure In the Journals

Hispanic veterans with HCV at higher risk for cirrhosis, HCC

September 1, 2014
Hispanic veterans with hepatitis C virus infection had a higher risk for developing cirrhosis or hepatocellular carcinoma compared with…
FDA News

FDA lifts clinical hold on vantictumab for NSCLC, breast cancer, pancreatic cancer

August 31, 2014
OncoMed Pharmaceuticals recently announced that the FDA has removed the partial clinical hold on enrollment in phase 1 clinical trials for the…
In the Journals

S-1 noninferior to UFT/LV for stage III colon cancer

August 29, 2014
Adjuvant chemotherapy with the oral fluoropyrimidine derivative S-1 conferred similar DFS rates as tegafur-uracil plus leucovorin among patients with…
figure In the Journals

Veterans with NAFLD-related HCC lacked surveillance before diagnosis

August 28, 2014
Veterans with hepatocellular carcinoma related to nonalcoholic fatty liver disease underwent surveillance at a lower rate compared with veterans with…
figure In the Journals

Low-risk adenoma removal associated with reduced colorectal cancer mortality

August 27, 2014
Patients who had low-risk adenomas removed demonstrated lower rates of long-term colorectal cancer mortality than those who had high-risk adenomas…
In the Journals

Barrett’s esophagus associated with increased risk for colon polyps

August 25, 2014
Individuals with Barrett’s esophagus demonstrated significantly increased risk for colon polyps, according to results of a case-control…
In the Journals

Tumor stage after neoadjuvant chemotherapy predicted post-surgery survival in esophageal adenocarcinoma

August 22, 2014
Tumor stage after neoadjuvant chemotherapy determined how long patients with esophageal and esophagogastric junction adenocarcinoma survived after…
figure In the Journals

Longer wait to liver transplantation associated with reduced HCC recurrence

August 20, 2014
Risk for hepatocellular carcinoma recurrence after liver transplantation was lower among patients who waited more than 120 days from exception to…
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