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No overall improvement in mCRC PFS with Y-90 spheres, but liver-only metastases respond well

July 7, 2015

Radiation therapy using yttrium-90 resin microspheres combined with chemotherapy did not improve overall progression-free survival in patients with nonresectable metastatic colorectal cancer. However, the combination regimen did improve survival in patients with liver-only metastases, according to newly published data on the SIRFLOX study.

“This … added treatment benefit [in patients with liver-only metastases] represents a significant 31% reduction in the risk of tumor progression in the liver for patients treated with SIR-Spheres Y-90 resin microspheres,” Guy A. van Hazel, MD, clinical professor of medicine at the University of Western Australia in Perth, Australia, said in a press release. “Our new analyses focused on the impact of two important factors on this treatment benefit.”

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No overall improvement in mCRC PFS with Y-90 spheres, but liver-only metastases respond well

July 7, 2015
Radiation therapy using yttrium-90 resin microspheres combined with chemotherapy did not improve overall progression-free survival in patients with…
Meeting News Coverage

Low BMI associated with shorter OS in mCRC patients

July 6, 2015
Metastatic colorectal cancer patients with low BMI had shorter overall survival than obese patients, according to a pooled analysis of Avastin…
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