Top Story

Celecoxib prevented colorectal polyps in children with familial adenomatous polyposis

October 21, 2014

PHILADELPHIA — Celecoxib reduced event rate and delayed progression of adenomas in children with familial adenomatous polyposis, known as FAP, when compared with placebo, according to phase 3 study data presented at the ACG Annual Scientific Meeting.

“Because of the burden of the disease on both the parent and the child, and this inexorable progression from polyps to cancer in individuals with FAP unless the colon is removed, we devised a study to look at the effect of an anti-inflammatory medication, celecoxib — which has been shown to reduce colon polyps in adults — for its effectiveness in children with FAP so we could delay the time to surgery or even obviate the need for surgery if shown to be extremely effective,” Carol A. Burke, MD, division of gastroenterology and hepatology at the Cleveland Clinic, told Healio.com/Gastroenterology.

figure Meeting News CoveragePerspective

Repeat exam of right colon with retroflexed, forward views achieved comparable adenoma detection

October 21, 2014
PHILADELPHIA — Adenoma detection rates in patients undergoing colonoscopy for colorectal cancer screening were similarly improved with a second examination of the…
figure In the Journals

Knowledge of individual risk did not increase colorectal cancer screening adherence

October 20, 2014
Receipt of individualized genetic and environmental risk assessments did not increase colorectal cancer screening rates, even among study participants whose assessments…
FDA News

FDA grants fast track designation to TAS-102 for mCRC

October 20, 2014
The FDA granted fast track designation to an investigational drug combination as a potential treatment for patients with refractory metastatic colorectal cancer, the…
CME CNE
figure

Treatment Decision-Making through the Spectrum of MDS: Case 3 Stem Cell Transplant for MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
More »
CME
figure

New Advances, New Options: Evaluating the Changing Landscape of Hemophilia to Optimize Patient Outcomes

This activity is supported by an educational grant from Biogen Idec.

The bleeding abnormalities associated with hemophilia can have devastating consequences for patients. Recent advances…
More »

Filter By:

figure Meeting News Coverage

Celecoxib prevented colorectal polyps in children with familial adenomatous polyposis

October 21, 2014
PHILADELPHIA — Celecoxib reduced event rate and delayed progression of adenomas in children with familial adenomatous polyposis, known as FAP…
figure Meeting News Coverage Perspective

Repeat exam of right colon with retroflexed, forward views achieved comparable adenoma detection

October 21, 2014
PHILADELPHIA — Adenoma detection rates in patients undergoing colonoscopy for colorectal cancer screening were similarly improved with a second…
figure In the Journals

Knowledge of individual risk did not increase colorectal cancer screening adherence

October 20, 2014
Receipt of individualized genetic and environmental risk assessments did not increase colorectal cancer screening rates, even among study…
FDA News

FDA grants fast track designation to TAS-102 for mCRC

October 20, 2014
The FDA granted fast track designation to an investigational drug combination as a potential treatment for patients with refractory metastatic…
In the Journals

Men at fourfold higher risk for esophageal adenocarcinoma

October 17, 2014
Men, particularly those with adenocarcinoma, have a significantly higher risk for developing esophageal cancer compared with women worldwide, with a…
In the Journals

Medicare reimbursement policy failed to significantly reduce chemotherapy cost

October 16, 2014
The Medicare Prescription Drug, Improvement and Modernization Act of 2003, intended to slow the skyrocketing costs of drugs the federal government…
Meeting News Coverage Perspective

Physician tumor board participation linked to clinical trial enrollment

October 14, 2014
Patients with lung or colorectal cancers whose physicians attended weekly multidisciplinary tumor board meetings were more likely to enroll in…
In the Journals

TACE, RFA led to favorable overall survival in recurring HCC

October 14, 2014
Patients who underwent radiofrequency ablation for residual or recurring hepatocellular carcinoma after transarterial chemoembolization showed…
figure In the Journals

Familial pancreatic cancer increased risk for other malignancies in kindred

October 14, 2014
Patients with familial pancreatic cancer were twice as likely to have a first-degree relative with an extra-pancreatic malignancy compared with…
figure In the Journals

Low levels of vitamin D increased risk for HCC

October 9, 2014
Individuals with insufficient or deficient levels of serum 25-hydroxyvitamin D were at increased risk for hepatocellular carcinoma, according to…
More Headlines »