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Despite promise, ‘maximum potential’ of precision medicine yet to be reached

Despite promise, ‘maximum potential’ of precision medicine yet to be reached
HemOnc Today, May 25, 2015

Precision medicine has garnered tremendous public attention since President Barack Obama established it as a national priority during his State of the Union address.

The Precision Medicine Initiative — created with an initial $215 million investment — is intended to help researchers determine which treatments best target specific characteristics of each individual patient’s disease. Leaders expect to gain insights from tissue samples, as well as biological, environmental, lifestyle and behavioral information provided by at least 1 million volunteers.

Steven A. Narod, MD, FRCPC In the Journals

Oophorectomy may decrease BRCA1-mutated breast cancer mortality

May 22, 2015
Women with ER-negative breast cancer who harbor BRCA1 mutations may experience a survival benefit from undergoing oophorectomy, according to the results of a…
Reshma Jagsi, MD, DPhil In the Journals

One-third of women with breast cancer desire genetic testing

May 21, 2015
Many women with nonmetastatic breast cancer expressed a strong desire for genetic testing, especially if they were younger or an ethnic minority, according to study…
In the Journals

Family history of breast cancer not prognostic for recurrence

May 20, 2015
A positive family history of breast cancer did not appear to increase the risk for poor outcomes in women with the disease, according to study results. Approximately 25%…
CME
Hematology Oncology Case Consults

Diagnosis and Management of Hemophilia

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of the patient with hemophilia supplemented with a case…
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Video
Immunotherapy trials show renewed application for breast cancer

Immunotherapy trials show renewed application for breast cancer

January 4, 2015
SAN ANTONIO — Douglas Yee, MD, director of the Masonic Cancer Center, as well as professor of medicine and…
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CME
New Advances, New Options: Evaluating the Changing Landscape of Hemophilia

New Advances, New Options: Evaluating the Changing Landscape of Hemophilia to Optimize Patient Outcomes

This activity is supported by an educational grant from Biogen Idec.

The bleeding abnormalities associated with hemophilia can have devastating consequences for patients. Recent advances…
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Arul M. Chinnaiyan, MD, PhD Cover StoryPublication Exclusive

Despite promise, ‘maximum potential’ of precision medicine yet to be reached

HemOnc Today, May 25, 2015
Precision medicine has garnered tremendous public attention since President Barack Obama established it as a national priority during his State of…
Steven A. Narod, MD, FRCPC In the Journals

Oophorectomy may decrease BRCA1-mutated breast cancer mortality

May 22, 2015
Women with ER-negative breast cancer who harbor BRCA1 mutations may experience a survival benefit from undergoing oophorectomy, according to the…
Reshma Jagsi, MD, DPhil In the Journals

One-third of women with breast cancer desire genetic testing

May 21, 2015
Many women with nonmetastatic breast cancer expressed a strong desire for genetic testing, especially if they were younger or an ethnic minority…
In the Journals

Family history of breast cancer not prognostic for recurrence

May 20, 2015
A positive family history of breast cancer did not appear to increase the risk for poor outcomes in women with the disease, according to study…
In the Journals

Loss of TGF-beta signaling in breast cancer impairs response

May 13, 2015
Below-normal amounts of the protein TGFBR2 may be predictive of breast cancer resistance to the anti-estrogen drug tamoxifen, according to study…
Joseph Ragaz, MD, FRCP CommentaryPublication Exclusive

The ‘puzzle’ of noncompliance: Skipped radiation and lives lost

HemOnc Today, May 10, 2015
Joseph Ragaz, MD, FRCP
Chu and colleagues report that as many as 35% of high-risk patients with breast cancer in the United States who have N2 to N3 locally advanced…
Katharine Yao In the Journals

Utilization of SLNB alone increased in early-stage breast cancer

May 11, 2015
A greater proportion of women with early-stage breast cancer underwent sentinel lymph node biopsy without axillary node dissection since the 2010…

How does obesity influence cancer risk?

May 7, 2015
An estimated 4% of cancers in men and 7% of cancers in women are associated with obesity, according to the NCI.People who are obese are at increased…
Katherine Gale, MD In the Journals

No increased oncologic risk associated with fat grafting in women with previous breast cancer

May 7, 2015
In women previously treated for breast cancer, researchers found no increased oncologic risk for local, regional or distant recurrences associated…
In the Journals

Most women with breast cancer begin treatment after delay

May 5, 2015
A majority of women with breast cancer are treated after a delay, and both patient and provider-related treatment delays were associated with…
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