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Benefits of tamoxifen for breast cancer prevention vary among at-risk women

February 26, 2015

Although most women who use tamoxifen for breast cancer prevention will derive benefit, more attention must be paid to the risk–benefit profiles of certain subgroups of at-risk women who may be more likely to experience serious side effects, according to study results.

These subgroups include older women, black women and women who have an intact uterus.

Ian H. Kunkler, MD In the Journals

Radiotherapy after surgery may be omitted in low-risk breast cancer

February 20, 2015
The addition of whole-breast irradiation to breast-conserving surgery conferred a modest but statistically significant reduction in risk for ipsilateral breast tumor…
In the Journals

Extra-virgin olive oil ingredient rapidly induces cancer cell death

February 19, 2015
Oleocanthal, an ingredient found in extra-virgin olive oil, induces cancer cell death without harming noncancerous cells, according to study results.“Compounds…
Beryl McCormick, MD In the JournalsPerspective

Radiotherapy benefits good-risk patients with DCIS after breast-conserving surgery

February 18, 2015
Radiotherapy may reduce the rate of local failure in patients with good-risk ductal carcinoma in situ, offering a better alternative to observation, according to results…
CME
New Advances, New Options: Evaluating the Changing Landscape of Hemophilia

New Advances, New Options: Evaluating the Changing Landscape of Hemophilia to Optimize Patient Outcomes

This activity is supported by an educational grant from Biogen Idec.

The bleeding abnormalities associated with hemophilia can have devastating consequences for patients. Recent advances…
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Meeting News Coverage Video
SOFT: Ovarian suppression reduced disease recurrence risk, increased menopausal symptoms

SOFT: Ovarian suppression reduced disease recurrence risk, increased menopausal symptoms

January 2, 2015
SAN ANTONIO — Beverly Moy, MD, MPH, clinical director of the breast oncology program at the Massachusetts…
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CME CNE
Stem Cell Transplant for AAMDS

Treatment Decision-Making through the Spectrum of MDS:
Case 3 Stem Cell Transplant for MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
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Hazel B. Nichols, PhD In the Journals

Benefits of tamoxifen for breast cancer prevention vary among at-risk women

February 26, 2015
Although most women who use tamoxifen for breast cancer prevention will derive benefit, more attention must be paid to the risk–benefit…
Ian H. Kunkler, MD In the Journals

Radiotherapy after surgery may be omitted in low-risk breast cancer

February 20, 2015
The addition of whole-breast irradiation to breast-conserving surgery conferred a modest but statistically significant reduction in risk for…
In the Journals

Extra-virgin olive oil ingredient rapidly induces cancer cell death

February 19, 2015
Oleocanthal, an ingredient found in extra-virgin olive oil, induces cancer cell death without harming noncancerous cells, according to study…
Beryl McCormick, MD In the JournalsPerspective

Radiotherapy benefits good-risk patients with DCIS after breast-conserving surgery

February 18, 2015
Radiotherapy may reduce the rate of local failure in patients with good-risk ductal carcinoma in situ, offering a better alternative to observation…
Navi B. Babak, MD In the Journals

Incident cancer linked to increased short-term stroke risk

February 17, 2015
Patients with a new cancer diagnosis have an elevated risk for subsequent stroke, according to study results.Babak Navi, MD, assistant professor of…
In the Journals

Model improves prediction of breast cancer risk after benign biopsy

February 16, 2015
A model that consisted of demographic and histologic features more accurately reflected a woman’s risk for breast cancer after receipt of a…
In the Journals

Researchers identify age-associated risks for gastric, breast cancers with CDH1 mutations

February 12, 2015
Age-associated risks for breast and gastric cancers in individuals who harbor CDH1 mutations in families who meet criteria for hereditary diffuse…
José Baselga, MD, PhD In the JournalsPerspective

Neoadjuvant HER-2–targeted breast cancer therapies less effective in patients with PIK3CA mutations

February 5, 2015
Patients with HER-2–positive breast cancer who harbored activating mutations in PIK3CA were considerably less likely to achieve total…
FDA News

FDA approves 3-D breast imaging system

February 4, 2015
The FDA has approved the Koning Breast CT, or KBCT, system and KBCT-guided biopsy bracket, the manufacturer announced today.KBCT (Koning Corp.) is…
Steven A. Narod, MD, FRCPC In the Journals

Breast cancer stage at diagnosis, survival vary by race, ethnicity

February 4, 2015
The likelihood that women with invasive breast cancer will be diagnosed at an early stage, as well as survival outcomes for those diagnosed with…
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