Topical tamoxifen noninferior to oral version for breast cancer treatment

  • July 25, 2014

A topical formulation of tamoxifen induced equally effective responses as oral tamoxifen for antiproliferative activity in ductal carcinoma in situ with reduced effects on endocrine and coagulation parameters, according to recent findings.

“Oral tamoxifen is used by some women at high risk for breast cancer to prevent the development of the disease, and our data suggest that gel application of tamoxifen could replace this approach, thus encouraging more women to adhere to preventive therapy,” researcher Seema A. Khan, MD, professor of surgery at Northwestern University Feinberg School of Medicine, said in a press release.

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