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Variation in risk for late mortality among pediatric cancer survivors can persist up to 20 years post-diagnosis

January 28, 2015

Although all survivors of pediatric cancer face increased risk for death, the risk is reduced as survivors age through childhood and young adulthood, according to study results.

“It is well established that survivors of childhood cancer have an elevated risk for late (>5 years from diagnosis) mortality compared with the general population,” researcher Gregory T. Armstrong, MD, MSCE, associate member in the department of epidemiology and cancer control at St. Jude Children’s Research Hospital and a HemOnc Today editorial board member, told HemOnc Today. “However, the current study utilized a large hospital-based cohort — [the] Childhood Cancer Survivor Study (CCSS) — as well as a large population-based cohort (SEER program) of survivors to identify that, as these children move farther from their primary cancer diagnosis — or at least out to 20 years in the current study — their 5-year mortality risk is progressively reduced.”

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