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Persistent HPV16 DNA in oral rinses predicts oropharyngeal cancer recurrence

July 31, 2015

Read the Perspective from Miriam N. Lango, MD

The presence of HPV type 16 DNA in oral rinses following treatment for HPV-related oropharyngeal cancer corresponded with poor prognosis and may serve as a potential biomarker for long-term tumor surveillance and local recurrence, according to results of a prospective cohort study.

The incidence of HPV-related oropharyngeal carcinoma (HPV-OPC) has increased in the U.S. and despite its favorable prognosis, recurrence occurs in 10% to 25% of cases. Gypsyamber D’Souza, PhD, MS, associate professor of cancer epidemiology at Johns Hopkins Bloomberg School of Public Health, and colleagues sought to determine whether HPV DNA detection in oral rinses following treatment for HPV-OPC served as a prognostic biomarker for recurrence and survival.

Raghu Kalluri, MD, PhD In the Journals

Blood particles may help detect early-stage pancreatic cancer

July 31, 2015
Glypicin-1 circulating exosomes may serve as a biomarker for the non-invasive detection for early-stage pancreatic cancer, according to study results.The detection of…
Darren Mays, PhD, MPH

Indoor tanning declines, but more melanoma prevention efforts urgently needed

July 31, 2015
Melanoma rates in the United States doubled between 1982 and 2011, according to a CDC report.“The sobering news is that, in 2011, there were more than 65,000 cases…

AAFP, ACP join nearly 600 other organizations in support of clinical data transparency

July 31, 2015
The American Academy of Family Physicians and the American College of Physicians has announced their support of the AllTrials campaign, joining 595 other organizations…
In the Journals

Researchers successfully transport blood samples via drones

July 31, 2015
Laboratory tests performed on blood samples flown for up to 40 minutes on hobby-sized drones yielded results comparable to those performed on samples that never left the…
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Tailored Therapies for Myelodysplastic Syndromes

Tailored Therapies for Myelodysplastic Syndromes

This activity is supported by an educational grant from Celgene Corporation.

Myelodysplastic syndromes (MDS) represent a group of myeloid clonal hemopathies with heterogeneous clinical…
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Meeting News Coverage Video
VIDEO: 'Care paths' may help manage rising cancer costs

VIDEO: 'Care paths' may help manage rising cancer costs

June 19, 2015
CHICAGO — Brian Bolwell, MD, chairman of Taussig Cancer Institute at Cleveland Clinic, discusses an abstract on…
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Hematology Oncology Case Consults

The Patient with Melanoma

No commercial support for this activity.

This CME activity will focus on the diagnosis and management of patients with melanoma.
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