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Aprepitant regimen reduced CINV in post-transplant myeloma

October 21, 2014

The addition of the NK-1 antagonist aprepitant to granisetron and dexamethasone reduced nausea and vomiting among patients with myeloma who underwent high-dose chemotherapy and autologous stem cell transplantation, according to results of a randomized, phase 3 trial.

The analysis included 362 patients with myeloma who melphalan conditioning followed by autologous stem cell transplantation at Heidelberg University Hospital in Germany. All patients were aged 18 years or older.

In the Journals

Everolimus–exemestane combination failed to significantly extend OS in advanced breast cancer

October 21, 2014
The addition of everolimus to exemestane extended OS in postmenopausal women with HR-positive, HER-2–negative advanced breast cancer, but the difference was not…
figure In the Journals

Knowledge of individual risk did not increase colorectal cancer screening adherence

October 20, 2014
Receipt of individualized genetic and environmental risk assessments did not increase colorectal cancer screening rates, even among study participants whose assessments…
FDA News

FDA grants fast track designation to TAS-102 for mCRC

October 20, 2014
The FDA granted fast track designation to an investigational drug combination as a potential treatment for patients with refractory metastatic colorectal cancer, the…
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CME CNE
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Treatment Decision-Making through the Spectrum of MDS: Case 2 High Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain to…
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Meeting News Coverage Video
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Nomogram predicted recurrence risk among women who underwent APBI

September 26, 2014
Jessica Wobb, MD, senior resident in radiation oncology at Beaumont Health System in Birmingham, Mich., describes how…
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CME CNE
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Treatment Decision-Making through the Spectrum of MDS: Case 1 Low Risk MDS

An educational presentation from Aplastic Anemia & MDS International Foundation.

MDS is a difficult disease to diagnose and treat. Frequently it is challenging for healthcare providers to explain MDS…
More »