July 1, 2015
Lactobacillus rhamnosus GG ATCC 53103 was associated with distinct, transient effects on anti-inflammatory pathways in gut microbiota among an elderly cohort, according to study results.
“There is great need to systematically study the effects of probiotic bacteria on the autochthonous microbial community in the human gut to further elucidate how these organisms confer beneficial outcomes to the host and substantiate commercial health claims,” Emiley A. Eloe-Fadrosh, PhD, of the Institute for Genome Sciences at the University of Maryland School of Medicine, and colleagues wrote. “The gut microbiota of elderly people provides a unique system to study the fitness landscape of the presumptive healthy, aging microbiota and assess the community stability and dynamics. We found that community composition was not modified due to probiotic intake; however, community-wide transcriptional changes were evident.”