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High-dose mesalamine effective as alternative induction therapy for mild-to-moderate Crohn's disease

High-dose mesalamine effective as alternative induction therapy for mild-to-moderate Crohn's disease
February 24, 2017

Among different induction therapies for mild-to-moderate Crohn’s disease, corticosteroids and high-dose budesonide were both effective, and high-dose mesalamine was an effective alternative, according to the results of a Bayesian network meta-analysis.

“Physicians and patients have many options in treating mild to moderately active Crohn’s disease,” Gilaad G. Kaplan, MD, MPH, from the departments of medicine and community health sciences at University of Calgary in Canada, told Healio Gastroenterology. “While corticosteroids are effective in treating Crohn’s disease, patients often prefer to avoid prednisone due to potential systemic toxicities.”

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