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Low serum sodium, high MELD score increased liver transplant survival

January 29, 2015

Liver transplant candidates with low serum sodium levels and a MELD score greater than 11 had an increased survival benefit after transplantation, according to new study data. 

“While the [Organ and Procurement Transplant Network] serum sodium allocation formula may reduce deaths on the wait-list by enhancing access to donor organs, it is not clear if candidates with hyponatremia gain any survival benefit over patients with normal sodium levels,” researcher Pratima Sharma, MD, MS, assistant professor in the division of gastroenterology, University of Michigan Health System, said in a press release. “Our study examines if patients with low serum sodium prior to liver transplant have a greater survival benefit than patients without low serum sodium, all other things being equal.”

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