February 11, 2016
Visceral sensitivity and severity of irritable bowel syndrome may be determined with the use of a nutrient and lactulose challenge test. The results of the test may also help characterize patients with IBS and help determine the efficacy of treatments.
In a prospective study, researchers examined 100 patients aged 18 to 65 years with IBS who were seen at Sahlgrenska Hospital, University of Gothenburg, Sweden, a secondary/tertiary care outpatient clinic. IBS diagnosis was based on the Rome III criteria, classification into subtypes was based on the Bristol Stool Form scale and IBS severity was assessed using patient questionnaires.