Rheumatology

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Factors of methotrexate-induced epidermal necrosis identified

May 23, 2017

Researchers identified early signs and risk factors of methotrexate-induced epidermal necrosis, and physicians should use caution when deciding when to prescribe methotrexate to high-risk patients, according to recently published study results in the Journal of the American Academy of Dermatology.

The researchers in Taiwan enrolled 24 patients with methotrexate-induced epidermal necrosis (MEN; mean age, 65.8 years; 13 men) and 150 methotrexate-tolerant controls (mean age, 40.7 years; 86 men) between 2007 and 2016. Demographics, pathology and plasma concentration of methotrexate were analyzed.

ACR issues statement after FDA releases guidance on biosimilar interchangeability

May 23, 2017
The American College of Rheumatology has issued a statement about the FDA’s draft guidance for biosimilar interchangeability. “The introduction of additional…
FDA News

FDA approves Kevzara for rheumatoid arthritis

May 23, 2017
After a resubmission by Sanofi and Regeneron Pharmaceuticals Inc., the FDA has approved Kevzara for the treatment of patients with rheumatoid arthritis, according to a…
FDA News

FDA approves Actemra for giant cell arteritis

May 22, 2017
The FDA has approved Actemra for the treatment of adults with giant cell arteritis. “Rheumatologists will finally have available an option for their patients…
CME CNE CPE CE

The Management of Comorbid Conditions in Patients with Rheumatoid Arthritis

Supported by an educational grant from Pfizer Inc.

Strong evidence demonstrates that patients with rheumatoid arthritis (RA) are at a high risk for developing several…
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GI Bookshelf

Chapter 5: Bowel Obstruction And Pseudo-Obstruction

From GI Emergencies: A Quick Reference Guide
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American Academy of Allergy, Asthma & Immunology Annual Meeting

American Academy of Allergy, Asthma & Immunology Annual Meeting

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VIDEO: Cush addresses management of methotrexate use in patients with RA

August 12, 2016
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In the Journals

Factors of methotrexate-induced epidermal necrosis identified

May 23, 2017
Researchers identified early signs and risk factors of methotrexate-induced epidermal necrosis, and physicians should use caution when deciding when…

ACR issues statement after FDA releases guidance on biosimilar interchangeability

May 23, 2017
The American College of Rheumatology has issued a statement about the FDA’s draft guidance for biosimilar interchangeability. “The…

FDA News

FDA approves Kevzara for rheumatoid arthritis

May 23, 2017
After a resubmission by Sanofi and Regeneron Pharmaceuticals Inc., the FDA has approved Kevzara for the treatment of patients with rheumatoid…

FDA News

FDA approves Actemra for giant cell arteritis

May 22, 2017
The FDA has approved Actemra for the treatment of adults with giant cell arteritis. “Rheumatologists will finally have available an option for…

In the Journals

Patients with psoriasis treated with biologics have minimal risk of hepatitis B, C reactivation

May 18, 2017
Patients with moderate-to-severe psoriasis without hepatitis who were seropositive for hepatitis B core antibody only or hepatitis C infection, and…

In the JournalsPerspective

Meta-analysis indicates NSAIDs linked with increased risk for heart attack

May 17, 2017
Researchers of this systematic review of studies from Canadian and European databases and a meta-analysis of individual patient data found NSAID use…

In the Journals

Study: Intra-articular triamcinolone not effective for symptomatic knee osteoarthritis

May 16, 2017
Intra-articular triamcinolone acetonide injections were no more effective than placebo saline injections for the reduction of pain in patients with…

In the Journals

Anti-hypertension diet linked with reduced risk for gout, Western diet linked with increased risk for gout

May 15, 2017
An anti-hypertension diet — that emphasizes fruits, vegetables, nuts, legumes, low fat dairy and whole grains and a low intake of sodium…

In the Journals

ACR issues statement on new FDA Commissioner Scott Gottlieb

May 10, 2017
The American College of Rheumatology has issued a statement regarding the confirmation of Scott Gottlieb as commissioner of the FDA, according to a…

Meeting News

Childhood obesity linked with increased risk for patellar cartilage defects in young adults

May 9, 2017
LAS VEGAS — Childhood weight, BMI and fat mass were linked with an increased risk for patellar cartilage defects in young adults, according to…

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