May 25, 2017
A postoperative drug regimen including cyclosporine after autologous noncultured melanocyte-keratinocyte cell transplant resulted in rapid and uniform repigmentation without any perilesional halo in patients with localized, stable vitiligo, according to study results published in Dermatologic Surgery.
Researchers studied 50 patients (mean age, 29.92 years; 32 females) who underwent autologous noncultured melanocyte-keratinocyte cell transplant for stable or resistant vitiligo at two dermatology centers in India. The patients were randomly divided into two groups of 25 patients each. Group 1 did not receive any postoperative treatment, and group 2 received postoperative cyclosporine at 3 mg.kg–1 d–1 for 3 weeks, then 1.5 mg.kg–1 d–1 for 6 weeks.