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MondoA protein presents potential new avenue for preventing type 2 diabetes

August 27, 2016

Blocking a cellular glucose sensor in muscle improves insulin responsiveness and provides a potential target for drugs to prevent type 2 diabetes, according to researchers.

“Our new study shows that a protein called MondoA may serve as a key link between insulin resistance and accumulation of fat in muscle, which occurs in obesity-related diabetes,” Daniel P. Kelly, MD, professor and director of Center for Metabolic Origins of Disease at Sanford Burnham Prebys Medical Discovery Institute, said in a press release. “This study is the first step towards testing MondoA-targeted drugs to prevent type 2 diabetes in preclinical studies.”

Top 5 diabetes stories, videos posted in the last month

August 26, 2016
Endocrine Today has compiled a list of the top five news reports and videos posted from July 25 to Aug. 25. Healio.com/Endocrinology readers were interested in a…
In the Journals

Prenatal BPA exposure may increase risk for anxiety, depression in boys

August 26, 2016
Greater prenatal exposure to Bisphenol A was associated with more depression and anxiety symptoms in boys aged 10 to 12 years but not girls, according to recent…
Meeting News CoverageVideo

VIDEO: Results of LEADER trial may have ‘huge impact’ on patients with diabetes

August 26, 2016
Results of the LEADER trial demonstrated that treatment with liraglutide compared with placebo in patients with type 2 diabetes not only decreased cardiovascular death…
In the Journals Plus

Low volumetric BMD tied to calcified atherosclerotic plaque progression in black adults

August 26, 2016
In black adults, the progression of calcified atherosclerotic plaque in the abdominal aorta is significantly associated with lower baseline volumetric bone mineral…
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Managing Obesity in 2015: Setting the Framework and Assessing All of the Options

This activity is supported by an educational grant from Novo Nordisk.

This CME activity is based on the slides and lectures presented by the faculty at the symposium, Managing Obesity in…
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Meeting News Coverage

VIDEO: Physicians, parents must be aware of type 1 diabetes signs before DKA

August 15, 2016
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ADA 2016

ADA 2016


Diabetic Retinopathy: The Importance of Early Screening, Referral, and Management

This activity is supported by an educational grant from Regeneron Pharmaceuticals, Inc.

Diabetic eye disease is one of the most common causes of vision loss in the United States. As the rates of diabetes…
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