Endocrinology

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Food sequence at meals can influence glucose control in type 2 diabetes

August 24, 2016

Adults with well-controlled type 2 diabetes who consumed non-glucidic foods prior to high-carbohydrate foods at mealtime saw reduced glucose variability over 2 months independent of weight loss, according to recent findings.

“This study demonstrates that by only manipulating the sequence of nutrient ingestion it is possible to improve glycemic excursions in type 2 diabetic patients in free-living conditions, and that this intervention is safe and well accepted,” Domenico Trico, of the department of clinical and experimental medicine at the University of Pisa in Rome, and colleagues wrote. “More in general, it proves the concept that it is effective and feasible to rely upon the physiologic responses acutely activated by nutrient ingestion (ie, nutrient sensing) to improve glucose homeostasis.”

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