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Type 2 diabetes may promote neurodegeneration independent of Alzheimer's disease

September 2, 2015

Cross-sectional analysis of the Alzheimer’s Disease Neuroimaging Initiative study cohort suggests type 2 diabetes may encourage neurodegeneration independent of Alzheimer’s disease dementia, and may be driven by tau phosphorylation.

“Type 2 diabetes mellitus is associated with a nearly 2-fold increased incident risk of dementia and [Alzheimer’s] disease dementia,” Chris Moran, MBBCh, of the Stroke and Aging Research Group at Monash University in Melbourne, Australia, and colleagues wrote. “Recently, we demonstrated that the association between [type 2 diabetes] and cognitive impairment in older age may primarily be driven by brain atrophy rather than cerebrovascular brain lesions, and that this atrophy occurs in cortical regions similar to those affected in [Alzheimer’s disease] dementia. However, there are limited data available from in vivo studies to determine whether [type 2 diabetes] contributes to the accumulation of [Alzheimer’s disease] pathology.”

Vitamin K antagonists do not affect bone mineral density, fracture risk In the Journals

Vitamin K antagonists do not affect bone mineral density, fracture risk

September 2, 2015
Vitamin K antagonists do not increase the risk for fracture or reduce bone mineral density, according to findings published in the Journal of Thrombosis and
In the Journals

Proton pump inhibitors may increase fracture risk in older women

September 2, 2015
Older women who use proton pump inhibitors to reduce stomach acid may increase their risk for fracture, according to research in Bone.In a prospective cohort study…
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Back-to-school reminder for parents and students: Check out college tax credits

September 2, 2015
With another school year here, the Internal Revenue Service reminds parents and students that now is a good time to see if they will qualify for either of two college…

Physicians support proposed biosimilar naming convention

September 2, 2015
In agreement with the FDA’s recent draft guidance on nonproprietary naming of biological products, six physician groups collectively sent a letter to CMS Acting…
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CME
Assessing Cornerstones for Successful Weight Loss

Assessing Cornerstones for Successful Weight Loss: Building a Foundation that Really Works

This activity is supported by an educational grant from Takeda Pharmaceuticals International, Inc., US Region and Orexigen Therapeutics, Inc.

Obesity has increased dramatically in the past 2 decades and is now considered a health care epidemic in the United…
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Meeting News Coverage Video
VIDEO: Chef integrates food and medicine in promotion of cardiometabolic health

VIDEO: Chef integrates food and medicine in promotion of cardiometabolic health

August 10, 2015
NEW ORLEANS — Chef Leah Sarris, program director at the Goldring Center for Culinary Medicine at Tulane…
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CME
Managing Today's EP Challenges with NOAC Use

Managing Today's EP Challenges with NOAC Use

This activity is supported by independent educational grants from Boehringer Ingelheim Pharmaceuticals, Inc. and Daiichi Sankyo, Inc.

This engaging activity featuring a superb faculty provides electrophysiologists and others with the best information…
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