June 29, 2015
In patients with coexisting primary hyperparathyroidism and renal disease, parathyroidectomy stopped the progression of renal function deterioration, according to recent findings in a retrospective cross-sectional study.
Francesco Tassone, MD, PhD, of Santa Croce and Carle Hospital in Cuneo, Italy, and colleagues evaluated the charts of 109 consecutive patients with primary hyperparathyroidism treated with parathyroidectomy between 1995 and 2012. The researchers extracted the following biochemistry data from the patient charts: BMI, systolic blood pressure, diastolic BP, creatinine, serum immunoreactive parathyroid hormone and 25-hydroxyvitamin D3 concentration. Participants also were tested with plain radiograph of the abdomen or ultrasound of the kidneys. The researchers used the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation to evaluate estimated glomerular filtration rate.