July 29, 2015
Adults with diabetes who skip breakfast increase their risk for postprandial hyperglycemia and an impaired insulin response that will continue even after eating lunch and dinner, according to research in Diabetes Care.
Daniela Jakubowicz, MD, of Wolfson Medical Center and Tel Aviv University in Israel, and colleagues analyzed data from 22 patients with type 2 diabetes for less than 10 years who had not completed shift work in at least 5 years (12 men; mean age, 57 years; mean BMI, 28.2 kg/m²; mean diabetes duration, 8.4 years; mean HbA1c, 7.7%) randomly assigned to 2 test days that included lunch and dinner, either with or without breakfast, between October 2012 and January 2014. Researchers, who provided all meals, measured postprandial plasma glucose, insulin, C-peptide, free fatty acids, glucagon and intact glucagon-like peptide (iGLP-1) after participants finished lunch and dinner on each test day. All test meals had the same macronutrient content and composition.