May 3, 2016
Hypoglycemia in hospitalized patients is associated with high insulin infusion rates and doses, and protocol deviations, according to study findings published in Endocrine Practice.
Amisha Wallia, MD, MS, assistant professor in the division of endocrinology, metabolism and molecular medicine at Northwestern University Feinberg School of Medicine, and colleagues evaluated 164 patients randomly assigned intensive insulin therapy (n = 82; target glucose, 140 mg/dL) or moderate insulin therapy (n = 82; target glucose 180 mg/dL) while hospitalized after liver transplantation to determine causes of inpatient hypoglycemia. Nine participants were excluded for non-insulin-related hypoglycemia. All participants had postoperative glucose level of at least 180 mg/dL and required an insulin drip. Patients were followed for 30 days or until discharge.