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Moxonidine therapy useful option for primary aldosteronism screening

March 22, 2017

In healthy, normotensive men, treatment with moxonidine therapy for 6 weeks resulted in a decrease in blood pressure without altering the aldosterone-to-renin ratio, minimizing the risk for false-positive results in screening for primary aldosteronism, according to findings from researchers in Australia.

“Currently, the most popular screening test for [primary aldosteronism] is the plasma aldosterone-to-renin ratio (ARR),” Ashraf H. Ahmed, MBBS, MSc, PhD, of the endocrine hypertension research center at the University of Queensland School of Medicine, and colleagues wrote. “Although considered the most reliable available screening approach, the ARR is not without false positives or negatives. ... Because most antihypertensive medications are known to affect the ARR, it is often necessary to withdraw such interfering agents to enable confident interpretation of results. ... The identification of additional medications that are free of appreciable effects on the ARR would therefore be very worthwhile.”

AMA urges members of Congress to oppose American Health Care Act

March 22, 2017
The American Medical Association today released a letter to members of Congress urging them to oppose the American Health Care Act, citing projections that it will cost…
In the Journals Plus

Statin use increases type 2 diabetes risk

March 22, 2017
Adults treated with statin therapy are at higher risk for developing type 2 diabetes vs. those not prescribed statin therapy, according to a meta-analysis of…

ACP: New amendments to AHCA ‘even less acceptable’

March 22, 2017
ACP recently sent a letter to the Congressional leadership in strong opposition of the manager’s amendments to the American Health Care Act, arguing that several…

Trump’s FDA pick brings ‘relief,’ but ties to industry criticized

March 22, 2017
When President Donald J. Trump nominated Scott Gottlieb, MD, to be the next FDA commissioner, the announcement was met with relief by some that the agency’s…
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Practical Lipidology®: Volume 3, Number 2

This activity is supported by an educational grant from Amgen

The reduction of low-density lipoprotein-cholesterol (LDL-C) is recognized as the primary strategy for decreasing…
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Meeting News

VIDEO: HR experts tackle hot topics from immigration to Generation Z

March 1, 2017
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Diabetic Retinopathy: Preferred Practice Patterns in Screening and Management

This activity is supported by an educational grant from Regeneron.

Diabetic retinopathy (DR) is a major cause of blindness among American adults aged 40 years and older. The prevalence…
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