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Bariatric surgery reverses hypogonadism in men with severe obesity

September 26, 2016

Men with severe obesity and hypogonadism who underwent Roux-en-Y gastric bypass surgery or sleeve gastrectomy saw increases in total testosterone and sex hormone-binding globulin levels at 1 month and 6 months after surgery, according to recent findings.

“Hypogonadism is prevalent in extremely obese men and can be reversed with weight loss after bariatric surgery,” Patchaya Boonchaya-anant, MD, professor of medicine at Chulalongkorn University in Bangkok, and colleagues wrote. “Increases in [total testosterone] and SHBG levels occurred early during rapid weight loss at 1 month after bariatric surgery, suggesting that insulin resistance plays a major role in [male obesity-associated secondary hypogonadism], though elevated estradiol levels persisted after bariatric surgery.”

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Phthalates, BPA may reduce vitamin D levels

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Environmental exposure to phthalates and bisphenol A may alter circulating levels of total 25-hydroxyvitamin D in adults, according to findings from a recent…
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Physicians debate ACGME's Milestones initiative

September 26, 2016
The Accreditation Council for Graduate Medical Education’s Milestones initiative and its role in internal medicine are a source of debate for physicians. …
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Guideline: Pump therapy, CGM recommended for type 1, type 2 diabetes

September 26, 2016
Insulin pump therapy and real-time, continuous glucose monitoring are recommended for people with both poorly controlled and well-controlled type 1 diabetes who are…
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Fully automated diabetes intervention improves physical activity, eating habits

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Adults with prediabetes assigned to a fully automated diabetes prevention program for 6 months showed improvements in physical activity and dietary variables vs. a…
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Practical Lipidology®: Volume 3, Number 1

This activity is supported by an educational grant from Amgen

The reduction of low-density lipoprotein-cholesterol (LDL-C) is recognized as the primary strategy for decreasing…
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VIDEO: Long-term oral bisphosphonate use mildly increases risk for osteonecrosis of the jaw

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The Emerging Biosimilar Therapeutic Landscape: Scientific Foundations and Clinical Implications

This activity is supported by an educational grant from Boehringer-Ingelheim Pharmaceuticals, Inc. and Lilly USA, LLC.

Recent processes have been established to facilitate the production, validation, and utilization of biosimilars…
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