November 21, 2014
In the first year after undergoing a lung transplant, most patients experience dysglycemia and may also be at significant risk for new-onset diabetes, according to recent findings.
In the prospective, longitudinal study, researchers evaluated 156 patients aged ≥16 years who underwent single, bilateral or heart-lung transplants at the Alfred Hospital in Australia between August 2010 and December 2012. Those patients not being treated for diabetes mellitus underwent screening with a standard 75-g oral glucose tolerance test (OGTT) with insulin levels. The researchers also measured HbA1c in all patients before lung transplant at 3, 12, and 24 months after transplant. The 2006 WHO criteria were used to diagnose diabetes, impaired glucose tolerance and impaired fasting glycemia.