Endocrinology

Top Story

EXSCEL: Exenatide meets primary safety objective for CV risk in type 2 diabetes

May 23, 2017

Top-line results from the EXSEL trial show the GLP-1 receptor agonist exenatide extended release met the primary safety objective of non-inferiority for major adverse cardiac events in patients with type 2 diabetes when compared with placebo, Astra Zeneca announced in a press release.

The Exenatide Study of Cardiovascular Event Lowering trial compared the effect of once-weekly exenatide extended release (Bydureon) added to usual care with placebo on the risk for the composite endpoint of CV death, non-fatal myocardial infarction or non-fatal stroke, in adults with type-2 diabetes at a wide range of CV risk. The EXSCEL trial is the largest and most inclusive patient population of any CV outcomes trial of the GLP-1 receptor agonist class conducted to date, including more than 14,000 patients from 35 countries, according to the release.

Meeting News

Replacing a single soda or beer with water daily reduces risk for obesity

May 23, 2017
Exchanging one serving of sugar-sweetened soft drink or one beer each day for a glass of water can lower the risk for obesity by 20%, according to data presented at the…
Meeting News

Swallowable intragastric balloon safe, effective in adults with obesity

May 23, 2017
In adults with obesity, a swallowable intragastric balloon combined with a very low-calorie ketogenic diet resulted in a mean weight loss of 15.2 kg without serious…
In the Journals Plus

Thyroid surgery complications more common than previously believed

May 22, 2017
Thyroid surgery-specific complications developed within 1 year of thyroid surgery in 12% of adults with differentiated or medullary thyroid cancer, and 6% developed…

Cybersecurity expert: 5 things physicians should consider to help protect data

May 22, 2017
In this guest commentary, Zuly Gonzalez, co-founder and CEO of Light Point Security and former cybersecurity expert at the National Security Agency, discusses what
More News Headlines »
CME CNE CE CE

Diabetic Retinopathy: Preferred Practice Patterns in Screening and Management

This activity is supported by an educational grant from Regeneron.

Diabetic retinopathy (DR) is a major cause of blindness among American adults aged 40 years and older. The prevalence…
More »
Video
Meeting News

VIDEO: Medical management for acromegaly offers hope for patients

April 6, 2017
More »
Featured
The Endocrine Society Annual Meeting

The Endocrine Society Annual Meeting

CME CNE CPE CE

The Future of the Lipid Panel: An NLA Expert Discussion

This educational activity is supported by an educational grant from Quest Diagnostics, Inc.

Past-President of the National Lipid Association and Editor-in-Chief of the Journal of Clinical Lipidology, Dr. W…
More »
Current Issues
View the Current Issue
Advertisement
Advertisement