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Low-dose HT similar to standard dose, placebo for some CV effects

January 27, 2015

In postmenopausal women undergoing hormone therapy, a low-dose regimen does not appear to differ from the standard dose or placebo in its effects on weight, BMI, blood pressure, C-reactive protein or HDL cholesterol, according to recent findings.

In the systematic review with meta-analysis, researchers evaluated 28 relevant randomized clinical trials with 3,360 patients published between January 1990 and August 2013 to determine the effect of low-dose estrogen HT compared with standard dose and placebo in postmenopausal women without an established cardiovascular disease.

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Testosterone therapy could benefit CV health, contrary to several studies

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