Endocrinology

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FDA grants breakthrough therapy designation to Azedra for pheochromocytoma, paraganglioma

July 28, 2015

The FDA granted breakthrough therapy designation to Ultratrace iobenguane I-131 for the treatment of patients with iobenguane-avid metastatic or recurrent pheochromocytoma and paraganglioma, according to a press release from the drug’s manufacturer.

Ultratrace iobenguane I-131 (Azedra, Progenics Pharma), a late-state radiotherapeutic drug candidate, is being evaluated in a phase 2b trial of patients with malignant pheochromocytoma or paraganglioma. Pheochromocytomas — rare tumors usually found within one or both adrenal glands — are referred to as paragangliomas when they arise in other areas of sympathetic nerve cells.

Childhood obesity increases during summer break

July 28, 2015
Obesity in children is likely to spike during the summer months, according to a recent press release. “The problem is actually greater in low-income, minority…
In the Journals

Childhood BMI, length at birth affect risk for type 2 diabetes

July 28, 2015
Adults with a low BMI at birth but high childhood BMI have increased odds of developing type 2 diabetes, as do adults with both a low BMI and short length at birth, even…
Barbara Bendlin In the Journals

Insulin resistance increases Alzheimer’s risk in middle-aged adults

July 27, 2015
Late middle-aged adults with insulin resistance may be at greater risk for developing Alzheimer’s disease, according to research in JAMA Neurology.In a…
James Floyd In the Journals

CV risk similar for second-line diabetes drugs plus metformin

July 27, 2015
Adults with type 2 diabetes using metformin combined with insulin have a similar cardiovascular risk when compared with adults using metformin combined with…
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CME
low no

Low- and No-Calorie Sweeteners in Weight Management: What Do You Need to Know?

This activity is supported by an educational grant from the American Beverage Association.

The use of low- and no-calorie sweeteners continues to grow as consumers continue to purchase foods and beverages…
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Meeting News Coverage Video
VIDEO: War on diabetes continues since founding in 1940

VIDEO: War on diabetes continues since founding in 1940

June 12, 2015
BOSTON — Samuel Dagogo-Jack, MD, discusses the war on diabetes declared in 1940 after an alarming 750,000…
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CME
Real-world Use of Anti-VEGF Therapy

Real-world Use of Anti-VEGF Therapy

This activity is supported by an educational grant from Genentech, Inc.

Anti-VEGF is well established as first-line therapy for the treatment of diabetic macular edema (DME) and age-related…
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