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CatD may be useful to differentiate pediatric liver inflammation, steatosis

March 4, 2015

Plasma cathepsin D levels could be used as noninvasive markers for distinguishing pediatric patients with steatosis from those with hepatic inflammation, according to newly published data in The American Journal of Gastroenterology.  

“We hypothesized that cathepsin D (CatD) levels in plasma may be altered in subjects with [nonalcoholic steatohepatitis] compared with subjects without NASH,” the researchers wrote. “Therefore, the aim of this study was to assess plasma levels of CatD in children with different stages of [nonalcoholic fatty liver disease] and to correlate these to histological criteria used for the diagnosis of NASH.”

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Shorter test for GH deficiency as accurate as traditional protocol

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HALIFAX, Nova Scotia — Clinicians can safely revise their growth hormone stimulation protocols to reduce the amount of sampling they perform when determining…
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Sex differences may reveal clues to psychiatric, neurologic conditions

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HALIFAX, Nova Scotia — The difference with which psychiatric and neurologic conditions affect the two sexes may provide clues to understanding the etiology of the…
In the Journals

Health coaching improves prescription concordance/adherence

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Patients with poorly controlled type 2 diabetes, hypertension or hyperlipidemia who received health coaching were more likely to have medication concordance compared…
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Cardiac MRI detects aortic dilation in pediatric Turner's syndrome

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HALIFAX, Nova Scotia — The use of cardiac MRI allows detection of cases of aortic dilation in pediatric patients with Turner’s syndrome, cases that were not…
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CME
Obesity Consults: Volume 2, Number 3

Obesity Consults: Volume 2, Number 3
Biology and Behavior

This activity is supported by an educational grant from Vivus, Inc and Eisai Co., Ltd.

Obesity is a complex, multifactorial disease. Understanding how psychology, genetics, biology and neurobiology…
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Autologous islet cell transplantation effective for chronic pancreatitis

December 3, 2014
In this video exclusive, Betul Hatipoglu, MD, clinical associate professor of medicine of the Endocrinology &…
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Low- and No-Calorie Sweeteners in Weight Management: What Do You Need to Know?

This activity is supported by an educational grant from the American Beverage Association.

The use of low- and no-calorie sweeteners continues to grow as consumers continue to purchase foods and beverages…
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