July 25, 2016
Women with polycystic ovary syndrome likely receive no benefit from daily omega-3 fatty acid supplementation, according to a meta-analysis of three randomized controlled trials.
“Reducing the levels of serum insulin and increasing insulin sensitivity are considered to be of paramount importance for therapeutic targets in PCOS,” Alirez Sadeghi, of the department of cellular and molecular nutrition at the School of Nutritional Sciences and Dietetics at Tehran University of Medical Sciences, Iran, and colleagues wrote. “Omega-3 fatty acids may lead to insulin sensitivity by producing and secreting anti-inflammatory adipokines, such as adiponectin, and also through reducing inflammation and proinflammatory cytokines. Although it is said that omega-3 fatty acids have positive effects on insulin resistance, various studies have indicated contradictory results.”