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‘Mini-dose’ glucagon viable option for hypoglycemia in type 1 diabetes

‘Mini-dose’ glucagon viable option for hypoglycemia in type 1 diabetes
February 10, 2016

Treatment with a “mini-dose” of ready-to-use, subcutaneous glucagon is an effective, alternative treatment for hypoglycemia in adults with type 1 diabetes, according to recent study findings.

“Mini-dose glucagon provides the opportunity to treat mild hypoglycemia without the consumption of additional calories, and may well avoid the problem of glycemic overshoot often observed with oral carbohydrate treatment of mild to moderate hypoglycemia, and without any nausea or other side effects associated with large doses of aqueous glucagon,” Morey W. Haymond, MD, professor of pediatrics and nutrition at Baylor College of Medicine in Houston, told Endocrine Today. “Having a liquid glucagon product that is stable at room temperatures over long periods of time, and in a ready-to-use device, will make this easy to use (not requiring reconstitution of lyophilized glucagon) and, hopefully, very patient acceptable.”

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