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Endogenous glucagon production less suppressed with OGTT vs. glucose infusion

August 23, 2016

Oral glucose tolerance testing results in less-suppressed endogenous glucagon production compared with isoglycemic intravenous glucose infusion in adults with and without diabetes, study data show.

Flip K. Knop, MD, PhD, of the Center for Diabetes Research, Gentofte Hospital, University of Copenhagen in Denmark, and colleagues evaluated 10 adults with type 2 diabetes (mean age, 57.1 years) and 10 matched controls (mean age, 56 years) without diabetes. Researchers sought to determine the differences in suppression of endogenous glucose production during OGTT and isoglycemic IV glucose infusion (IIGI).

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