Collaboration of physicians behind first observations of Prader-Willi syndrome
Andrea Prader and Heinrich Willi, two Swiss pediatricians, and Alexis Labhart, an internist, first described Prader-Labhart-Willi Syndrome in 1956.
Prader was an influential figure in European pediatrics and is considered one of the founding fathers of endocrinology. Willi was a prominent pediatrician and had a notable career in Zurich. Labhart was a Swiss investigator and medical professor born in Russia, who eventually became the head of the metabolic unit and professor of internal medicine at the University of Zurich.
Together, they published the first report on what is known today as Prader-Willi Syndrome. In the report they described children with abnormalities including diminished fetal activity, feeding difficulties in infancy, poor muscle tone, underdeveloped sex organs, short stature, small hands and feet, cognitive impairment and a propensity to develop diabetes in adolescence and adulthood. <1.9 mU/L. More »