Reproduction/Androgen Disorders

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Leptin levels tied to weight gain in central precocious puberty

February 9, 2017

In girls with central precocious puberty, elevated leptin levels at diagnosis may be a risk factor for increased BMI z score over the next year, study data show.

Jessie N. Zurita-Cruz, MD, MSc, from the unit for medical research in clinical epidemiology, National Medical Center XXI Century, Mexican Institute of Social Security, and colleagues evaluated 42 girls (median age, 7.2 years; median BMI z score, 1.14; median bone age, 10.5 years) with central precocious puberty; 26 in Tanner breast stage 2 and 16 in breast stage 3. Participants were evaluated at the time of diagnosis (baseline) and 12-month follow-up. Researchers sought to determine whether serum leptin levels are related to BMI z score.

In the Journals Plus

Metformin improves clinical outcomes in PCOS, not metabolic, endocrine outcomes

February 8, 2017
Women with polycystic ovary syndrome assigned metformin therapy saw improved clinical outcomes, including reduced BMI, waist-to-hip ratio and blood pressure, compared…
In the Journals Plus

Obesity in couples may decrease fertility rates

February 3, 2017
Couples with overweight and obesity had reduced fertility rates compared with couples with normal weight, suggesting the importance of body composition when couples are…
In the Journals Plus

Adults with differences of sex development report poorer psychological well-being

February 2, 2017
Adults with differences of sex development did not appear to experience a reduced health-related quality of life, but they reported impaired psychological well-being
CME

Improving Bone Strength and Reducing Fracture Risk in Osteoporosis

This activity is supported by an educational grant from Merck & Co., Inc.

Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue leading to reduced…
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VIDEO: Forced gene expression produces PCOS phenotype

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New Treatment Paradigms for Diabetic Retinopathy: Current Status and Applications for Practice

This activity is supported by an educational grant from Genentech, Inc.

Despite a number of effective treatment options, diabetic eye disease is a leading cause of vision loss in the United…
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In the Journals PlusAbstract Only

Salivary Testosterone during the Minipuberty of Infancy

February 14, 2017
AUTHORS:
Contreras M, et al.

In the Journals Plus

Leptin levels tied to weight gain in central precocious puberty

February 9, 2017
In girls with central precocious puberty, elevated leptin levels at diagnosis may be a risk factor for increased BMI z score over the next year…

In the Journals Plus

Metformin improves clinical outcomes in PCOS, not metabolic, endocrine outcomes

February 8, 2017
Women with polycystic ovary syndrome assigned metformin therapy saw improved clinical outcomes, including reduced BMI, waist-to-hip ratio and blood…

In the Journals Plus

Obesity in couples may decrease fertility rates

February 3, 2017
Couples with overweight and obesity had reduced fertility rates compared with couples with normal weight, suggesting the importance of body…

In the Journals Plus

Adults with differences of sex development report poorer psychological well-being

February 2, 2017
Adults with differences of sex development did not appear to experience a reduced health-related quality of life, but they reported impaired

In the Journals PlusAbstract Only

Health-related Quality of Life and Psychological Wellbeing in Adults with Differences of Sex Development (DSD)

January 26, 2017
AUTHORS:
Bennecke E, et al.

In the Journals PlusPerspective

Timing of menarche linked to premature, early menopause risk

January 25, 2017
The risk for premature or early menopause is increased among women who experienced menarche at an early age and did not give birth to any children…

In the Journals Plus

Salivary testosterone measurements mirror serum testosterone findings

January 24, 2017
Among a general population sample in Britain, morning salivary testosterone measured by liquid chromatography-tandem mass spectrometry produced…

In the Journals Plus

Metformin superior to myoinositol for metabolic parameters in PCOS

January 18, 2017
Women with polycystic ovary syndrome and overweight or obesity experienced greater improvements in hormonal, clinical and metabolic parameters after…

In the Journals Plus

Coenzyme Q10 supplementation alters glucose metabolism, lipids in women with PCOS

January 16, 2017
Women with polycystic ovary syndrome assigned to 12 weeks of coenzyme Q10 supplementation saw an improvement in glucose profile and total cholesterol…

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