Academic Societies’ Annual Meeting 2011
Increased knowledge about cystic fibrosis-related diabetes did not
correlate with better adherence to recommendations for management among
children with the disease, according to the results of a recent survey.
To gain insight into patients’ knowledge about
fibrosis-related diabetes, researchers at the Rainbow Babies and
Children’s Hospital in Cleveland developed the Cystic Fibrosis Diabetes
Knowledge Survey. Participants were asked about the pathophysiology, symptoms,
management and complications associated with the disease.
The researchers included 32 patients with cystic fibrosis-related
diabetes and 33 patients without the disease, all of whom were aged 14 years or
older. Results indicated that patients with cystic fibrosis-related diabetes
had considerably higher knowledge scores than those without (83% vs. 72.2%;
P<.001). Higher scores in this group also correlated with lower age
(P=.01) and lower BMI (P=.008), according to the researchers.
However, no relationship was observed between knowledge scores and
levels, forced expiratory volume or duration of disease.
Despite receiving information on symptoms, management and complications,
25% of patients were not educated about how to diagnose cystic fibrosis-related
diabetes or its effects on pulmonary status. Further, survey results indicated
that at least 25% of patients were unaware of the potential relationship
between poor management of the condition and lower pulmonary function tests and
The researchers reported a negative correlation between adherence to
diabetes care and the HbA1c levels of patients with cystic fibrosis-related
diabetes (P=.0064) and a positive correlation between adherence and BMI
(P=.02). However, data also suggested that adherence score correlated
negatively with knowledge score (P=.01).
“Our surveys identified that adherence, but not diabetes knowledge,
correlated with better glycemic control,” the researchers wrote. “We
have identified gaps in diabetes knowledge, especially relating [cystic
fibrosis-related diabetes] to weight and pulmonary status, which will guide
improvements in [cystic fibrosis-related diabetes] education.”
For more information:
- Kaminski B.
Poster 2938.407. Poster session: Endocrinology &
diabetes. Presented at: Pediatric Academic Societies 2011; April 30-May 3,
It is not surprising that adherence to the diabetes regimen correlates
with better glycemic control and nutritional status in patients with cystic
fibrosis-related diabetes. The researchers have determined that approximately
28% of cystic fibrosis adolescents and adults without diabetes and 17% of those
with diabetes at their institution do not understand the role that cystic
fibrosis-related diabetes plays in cystic fibrosis clinical decline. Given the
critical relation that emerges during adolescence between cystic
fibrosis-related diabetes and increased morbidity and mortality from pulmonary
disease, they have identified a target area for their educational efforts.
– Antoinette Moran, MD
Division Chief, Pediatric Endocrinology
University of Minnesota