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Sulfonylurea therapy improves neurologic symptoms in children with neonatal diabetes

October 8, 2015

Children with certain developmental delays associated with neonatal diabetes showed measurable improvement in their symptoms after switching from insulin therapy to sulfonylurea therapy for 12 months, according to research in Diabetes Care.

In a prospective, single-center study of children successfully switched from insulin to sulfonylurea therapy for 12 months, researchers found that the sulfonylurea glyburide improved central nervous system function in children with permanent or transient neonatal diabetes due to KCNJ11 or ABCC8 mutations.

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