Neuroendocrinology

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Lag time between multiple endocrine neoplasia diagnoses linked to morbidity, mortality

January 19, 2016

In families affected by multiple endocrine neoplasia type 1, the lag time between diagnosis of the index case and diagnosis of other family members may lead to negative outcomes, including death, for the non-index cases, according to recent findings.

Gerlof D. Valk, MD, PhD, of the University Medical Centre Utrecht in the Netherlands, and colleagues evaluated 393 participants aged older than 16 years from the Dutch MEN1 Study group. During the interval between 1990 and 2014, researchers collected data for all patients from every quarter of each available year; family relationships were noted in the medical records.

In the Journals

Multiple, secondary hormone secretion in PNETs linked to morbidity, mortality

December 17, 2015
A minority of patients display a diversity of pancreatic neuroendocrine tumor hormone secretion at tumor diagnosis or during the course of their disease.These patients…
Imaging AnalysisPublication Exclusive

Middle-aged man diagnosed with giant invasive prolactinoma

Endocrine Today, November 2015
Stephanie L. Lee, MD PhD ECNU
A 52-year-old man was referred to our clinic for the evaluation and management of a large pituitary mass. He went to the ED reporting 2 months of worsening intermittent…
In the Journals

Estrogen priming may improve HPO axis function in women with obesity

October 28, 2015
In ovulating women with obesity, estrogen priming appears to yield improvements in hypothalamic-pituitary-ovarian axis function and proinflammatory profiles, according…
In the Journals

Lag time between multiple endocrine neoplasia diagnoses linked to morbidity, mortality

January 19, 2016
In families affected by multiple endocrine neoplasia type 1, the lag time between diagnosis of the index case and diagnosis of other family members…
In the Journals

Multiple, secondary hormone secretion in PNETs linked to morbidity, mortality

December 17, 2015
A minority of patients display a diversity of pancreatic neuroendocrine tumor hormone secretion at tumor diagnosis or during the course of their…
Imaging AnalysisPublication Exclusive

Middle-aged man diagnosed with giant invasive prolactinoma

Endocrine Today, November 2015
Stephanie L. Lee, MD PhD ECNU
A 52-year-old man was referred to our clinic for the evaluation and management of a large pituitary mass. He went to the ED reporting 2 months of…
In the Journals

Estrogen priming may improve HPO axis function in women with obesity

October 28, 2015
In ovulating women with obesity, estrogen priming appears to yield improvements in hypothalamic-pituitary-ovarian axis function and proinflammatory…
In the Journals

Age of diagnosis, rate of BMI increase associated with mortality rate for hypothalamic obesity in children

October 22, 2015
An increase in BMI following 6 months of therapy for a hypothalamic tumor in children is a risk factor for mortality caused by hypothalamic obesity…
In the Journals

Pre-pubertal, mid-pubertal children more sensitive to evening light exposure

August 25, 2015
Children in early to mid-puberty are prone to evening light sensitivity and suppressed melatonin levels, potentially leading to disrupted sleep…
In the Journals

Somatuline Depot safe, well tolerated in patients with acromegaly

August 20, 2015
Adults with acromegaly controlled with octreotide therapy achieved normal insulin-like growth factor I levels when assigned Somatuline Depot at…
Imaging AnalysisPublication Exclusive

‘The worst headache of my life’

Endocrine Today, July 2015
Elizabeth Herman, MD; Stephanie L. Lee, MD, PhD, ECNU
A 30-year-old man was referred for evaluation of a pituitary mass. The patient reported he was previously well until he developed a severe…
In the Journals

Conservative management effective for primary hypophysitis

June 22, 2015
Unless symptoms are severe or progressive, conservative management is the recommended choice for primary hypophysitis, according to recent study…
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VIDEO: Screening for Cushing's critical, complicated

May 20, 2015
NASHVILLE. Tenn. — In this video exclusive, Maria Fleseriu, MD, FACE, of Oregon Health & Science University, discusses Cushing’s…
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