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FDA approves Somatuline Depot for gastroenteropancreatic neuroendocrine tumors

December 16, 2014

The FDA today approved lanreotide for treatment of patients with unresectable, well- or moderately differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors.

The approval was based in part on results of a trial that included 204 patients with non-functioning gastroenteropancreatic neuroendocrine tumors. More than half of the patients (55%) had tumors that were outside of the pancreas.

Signifor long-acting release wins FDA approval for acromegaly treatment

December 16, 2014
The FDA has approved a long-acting release formulation of pasireotide to treat patients with acromegaly who have either not responded to surgery or for whom surgery…
In the Journals

Metabolic effects of TNF-a depend on intact pituitary function

December 12, 2014
With infusion of tumor necrosis factor-alpha, healthy men had greater increases in urea and amino acid fluxes and endogenous glucose production than men with…
Meeting News Coverage

PET/CT neuroimaging reveals pituitary abnormalities in veterans with PTSD

December 4, 2014
Hybrid neuroimaging of the pituitary region of the brain could help distinguish military veterans with posttraumatic stress disorder from those with mild traumatic brain…
CME
Acromegaly: Challenges in Diagnosis - Part 2 of 5

Acromegaly: Challenges in Diagnosis - Part 2 of 5

This activity is supported by an educational grant from Genentech.

The diagnosis of acromegaly is often not made until 7 to 10 years after symptom onset. Contributing factors include low…
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CME
low no

Low- and No-Calorie Sweeteners in Weight Management: What Do You Need to Know?

This activity is supported by an educational grant from the American Beverage Association.

The use of low- and no-calorie sweeteners continues to grow as consumers continue to purchase foods and beverages…
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FDA approvals

FDA approves Somatuline Depot for gastroenteropancreatic neuroendocrine tumors

December 16, 2014
The FDA today approved lanreotide for treatment of patients with unresectable, well- or moderately differentiated, locally advanced or metastatic…

Signifor long-acting release wins FDA approval for acromegaly treatment

December 16, 2014
The FDA has approved a long-acting release formulation of pasireotide to treat patients with acromegaly who have either not responded to surgery…
In the Journals

Metabolic effects of TNF-a depend on intact pituitary function

December 12, 2014
With infusion of tumor necrosis factor-alpha, healthy men had greater increases in urea and amino acid fluxes and endogenous glucose production than…
Meeting News Coverage

PET/CT neuroimaging reveals pituitary abnormalities in veterans with PTSD

December 4, 2014
Hybrid neuroimaging of the pituitary region of the brain could help distinguish military veterans with posttraumatic stress disorder from those with…
In the JournalsPerspective

Gleason score associated with time to development of neuroendocrine prostate cancer

November 25, 2014
Gleason scores among patients with conventional prostatic adenocarcinoma was significantly associated with time to development of treatment-related…
In the Journals

Acromegaly diagnosis treatment, guideline issued by The Endocrine Society

November 4, 2014
A new clinical practice guideline developed by The Endocrine Society and published the Journal of Clinical Endocrinology & Metabolism addresses…
In the Journals

Mutations in patients with MEN1 increased risk for malignancy, death

October 29, 2014
Patients with multiple endocrine neoplasia type 1 who have mutations leading to a loss of interaction with certain domain codons may be at higher…
In the Journals

Ghrelin paralleled adiposity increase after acromegaly surgery

September 11, 2014
The rise in total ghrelin found to accompany some remaining cardiovascular risk markers and adiposity increase in patients with acromegaly remission…
David Llewellyn In the Journals

Vitamin D deficiency increased dementia, Alzheimer's disease risk

August 7, 2014
Vitamin D deficiency is associated with an increased risk for dementia and Alzheimer’s disease, according to recent study findings published in…
In the Journals

Caffeine may lead to more bothersome vasomotor symptoms

August 1, 2014
The intake of caffeine was positively associated with more bothersome vasomotor symptoms in postmenopausal women, according to research published in…
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