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Weight sexual libido unchanged with lowdose paroxetine to treat vasomotor symptoms

October 20, 2014

Read the Perspective from R. Jane Lau, MD

Paroxetine administered in low doses to treat vasomotor symptoms associated with menopause did not yield significant changes in body weight or sexual function, according to pooled phase 3 results published in Menopause.

The findings came from two randomized, placebo-controlled trials looking at the effects of paroxetine 7.5 mg (Brisdelle, Noven Therapeutics), a selective serotonin reuptake inhibitor (SSRI), on postmenopausal women with moderate to severe vasomotor systems during 4, 12 and 24 weeks.

Meeting News Coverage

Lower estradiol, SHBG levels related to ectopic CV fat volumes in women at midlife

October 20, 2014
WASHINGTON — Endogenous sex hormones were associated with ectopic cardiovascular fat volumes in women during varying stages of menopause, according to data…
Meeting News Coverage

DXA to determine body fat may better evaluate metabolic syndrome

October 17, 2014
WASHINGTON — Using DXA to determine body fat percentage expressed as a percentile for age and sex may be a reasonable, safe and simple approach to evaluate…
In the Journals

GH therapy offered long-term improvement in quality of life at all ages

October 8, 2014
Growth hormone replacement therapy provided sustained improvement in quality of life for adults and children with deficiencies, according to research published in The
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Screening and Treatment of Diabetes-Associated Eye Disease: Out of Sight, Out of Mind?

This activity is supported by an educational grant from Regeneron Pharmaceuticals, Inc.

Diabetic retinopathy is a major cause of blindness among adults aged 40 years and older. Optimal outcomes necessitates…
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Acromegaly: Pathophysiology, Signs, Symptoms, and Complications - Part 1 of 5

This activity is supported by an educational grant from Genentech.

An understanding of the pathophysiological mechanisms of acromegaly is important to its various complications as well…
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In the Journals Perspective

Weight sexual libido unchanged with lowdose paroxetine to treat vasomotor symptoms

October 20, 2014
Paroxetine administered in low doses to treat vasomotor symptoms associated with menopause did not yield significant changes in body weight or sexual…
Meeting News Coverage

Lower estradiol, SHBG levels related to ectopic CV fat volumes in women at midlife

October 20, 2014
WASHINGTON — Endogenous sex hormones were associated with ectopic cardiovascular fat volumes in women during varying stages of menopause…
Meeting News Coverage

DXA to determine body fat may better evaluate metabolic syndrome

October 17, 2014
WASHINGTON — Using DXA to determine body fat percentage expressed as a percentile for age and sex may be a reasonable, safe and simple approach…
In the Journals

GH therapy offered long-term improvement in quality of life at all ages

October 8, 2014
Growth hormone replacement therapy provided sustained improvement in quality of life for adults and children with deficiencies, according to research…
FDA News

Bioequivalent estradiol patch approved for new indication dose

September 27, 2014
The FDA has approved a 33% smaller dose of the estradiol transdermal system for the prevention of postmenopausal osteoporosis, according to the…
Meeting News Coverage

FDA committees withhold approval of oral testosterone therapy

September 19, 2014
COLLEGE PARK, MD — On day 2 of a joint meeting on testosterone replacement therapies, the Bone, Reproductive and Urologic Drugs and Drug Safety…
FDA News Perspective

FDA committees near-unanimous on need to investigate testosterone therapies

September 18, 2014
COLLEGE PARK, MD — Two FDA advisory committees voted 20-1 in favor of revising the current indication for testosterone replacement therapies…
figure FDA News Perspective

Advisory Committee recommends approval of PTH therapy for hypoparathyroidism

September 15, 2014
After a debate-filled meeting today, the Endocrinologic and Metabolic Drugs Advisory Committee voted 8 to 5 in favor of approval for recombinant…
In the Journals

Microbe diversity may influence estrogen metabolism, reduce breast cancer risk in postmenopause

September 12, 2014
Women with greater diversity of gut microbiota appear to have an elevated urinary ratio of hydroxylated estrogen metabolites to parent estrogen…
figure In the Journals

Testosterone, estradiol levels could help predict sudden cardiac arrest

September 4, 2014
Assessing sex hormone levels could help identify people who are at an increased risk for sudden cardiac arrest, according to research published in…
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