Hormone Therapy

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C-peptide reliably predicts insulin secretion in children with GH deficiency

May 20, 2016

In children with growth hormone deficiency, C-peptide measurements provide a better estimate of insulin secretion than insulin levels throughout the first 12 months of growth hormone therapy, according to recent study findings.

“Given the insulin antagonist action of GH, in addition to the direct stimulatory effect on beta cell, GH [therapy] can lead to glucose metabolism impairment through decreased insulin sensitivity and impaired pancreatic beta-cell function,” Alessandro Ciresi, of the biomedical department of internal and specialist medicine at the University of Palermo, Italy, and colleagues wrote. “Therefore, a reliable evaluation of the insulin secretion in GH-[deficient] children during GH [therapy] is very important.”

In the Journals

Younger age at HT initiation decreases CHD mortality risk

May 16, 2016
Women who are younger than 60 years when they begin estradiol-based hormone therapy have a reduced risk for coronary heart disease mortality, according to study…
In the Journals

Testosterone therapy duration associated with mortality, CV events

May 11, 2016
Short-duration testosterone replacement therapy in older men was associated with increased risks for mortality and cardiovascular events, whereas longer duration therapy…
In the Journals

Nebido improves sexual function in severe hypogonadism

May 10, 2016
Men with severe hypogonadism reported improved sexual function after testosterone replacement therapy with Nebido, study results show.However, sexual function scores for…
CME

Avoiding “Loss of Chance”… Improving the Screening, Treatment, and Referral of Patients with Diabetic Retinopathy

This activity is supported by an educational grant from Genentech, Inc.

Despite a number of effective treatment options, diabetic eye disease is a leading cause of vision loss in the United…
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Meeting News Coverage

Video: Low kisspeptin could identify risk for miscarriage in asymptomatic women

June 21, 2014
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Highlights from AACE

Highlights from AACE

CME

Diabetic Retinopathy: The Importance of Early Screening, Referral, and Management

This activity is supported by an educational grant from Regeneron Pharmaceuticals, Inc.

Diabetic eye disease is one of the most common causes of vision loss in the United States. As the rates of diabetes…
More »
In the Journals

C-peptide reliably predicts insulin secretion in children with GH deficiency

May 20, 2016
In children with growth hormone deficiency, C-peptide measurements provide a better estimate of insulin secretion than insulin levels throughout the…

In the Journals

Younger age at HT initiation decreases CHD mortality risk

May 16, 2016
Women who are younger than 60 years when they begin estradiol-based hormone therapy have a reduced risk for coronary heart disease mortality…

In the Journals

Testosterone therapy duration associated with mortality, CV events

May 11, 2016
Short-duration testosterone replacement therapy in older men was associated with increased risks for mortality and cardiovascular events, whereas…

In the Journals

Nebido improves sexual function in severe hypogonadism

May 10, 2016
Men with severe hypogonadism reported improved sexual function after testosterone replacement therapy with Nebido, study results show.However, sexual…

In the Journals

Low testosterone may raise diabetes risk

May 1, 2016
In male mice, androgen receptor deficiency in beta cells impairs glucose-stimulated insulin secretion, increasing the risk for developing type 2…

In the Journals

Children with Silver-Russell syndrome gain height with growth hormone therapy

April 21, 2016
Growth hormone therapy appears to yield height increases in children with Silver-Russell syndrome comparable to those gained by treated children…

In the Journals

GH treatment outcomes may be impaired by vitamin D status

April 12, 2016
Adults with growth hormone deficiency may need to maintain adequate levels of vitamin D to reach optimal effect of growth hormone therapy on bone…

Meeting News Coverage

Custom-compounded hormones linked to risks, side effects in menopausal women

April 7, 2016
BOSTON — Clinicians should avoid prescribing custom-compounded bioidentical hormones for the treatment of menopausal symptoms due to the…

Meeting News CoverageVideo

VIDEO: Testosterone Trials results announcement met with anticipation

April 7, 2016
BOSTON — In this video exclusive, Tamara Wexler, MD, PhD, director of the pituitary center at New York University Langone, give her…

Meeting News Coverage

Testosterone therapy plus very low calorie diet prevents lean mass loss in men

April 4, 2016
BOSTON — Healthy men with obesity and low testosterone randomly assigned testosterone therapy combined with a very low calorie diet maintained…

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