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Orphan drug shows promise in Prader-Willi syndrome

March 28, 2015

Ten weeks of therapy with a diazoxide choline controlled-release tablet appeared to help control hyperphagia and reduce antisocial behaviors associated with Prader-Willi syndrome, according to a press release from the drug’s developer, Essentialis, Inc.

Diazoxide choline was granted orphan status for the treatment of Prader-Willi syndrome (PWS) by the FDA in May of last year.

In the Journals

HT may reduce mortality risk in statin-treated postmenopausal women

March 20, 2015
In women treated with statins, hormone therapy appears to decrease the risk for death from any cause, according to research published in Menopause. Although lifestyle…
In the Journals

Oral melatonin may benefit sleep-deprived ICU patients

March 20, 2015
Melatonin could offer more and better quality sleep compared with earplugs and eye masks after exposure to environments with high levels of noise and light, according to…
Henry Boardman In the Journals

Hormone therapy offers no CV protection for postmenopausal women, may increase stroke risk

March 13, 2015
Hormone replacement therapy does not protect postmenopausal women against cardiovascular disease and may increase their risk for stroke and venous thromboembolic events…
CME
Obesity Consults: Volume 2, Number 4 Obesity and the Cardiovascular System

Obesity Consults: Volume 2, Number 4
Obesity and the Cardiovascular System

This activity is supported by an educational grant from Eisai, Inc. and Vivus, Inc.

Obesity is associated with a wide range of comorbid conditions, including diabetes, hypertension, sleep apnea, and…
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Obesity Consults

Obesity Consults: Volume 2, Number 5
Practical Guide to Medications Approved for Chronic Weight Management

Several pharmacologic options for the management of obesity have been approved by the US FDA, giving clinicians a range…
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Orphan drug shows promise in Prader-Willi syndrome

March 28, 2015
Ten weeks of therapy with a diazoxide choline controlled-release tablet appeared to help control hyperphagia and reduce antisocial behaviors…
In the Journals

HT may reduce mortality risk in statin-treated postmenopausal women

March 20, 2015
In women treated with statins, hormone therapy appears to decrease the risk for death from any cause, according to research published in…
In the Journals

Oral melatonin may benefit sleep-deprived ICU patients

March 20, 2015
Melatonin could offer more and better quality sleep compared with earplugs and eye masks after exposure to environments with high levels of noise and…
Henry Boardman In the Journals

Hormone therapy offers no CV protection for postmenopausal women, may increase stroke risk

March 13, 2015
Hormone replacement therapy does not protect postmenopausal women against cardiovascular disease and may increase their risk for stroke and venous…
Charles Tegeler In the Journals

Noninvasive neurotechnology relieves menopause-related symptoms

March 13, 2015
Women in midlife experienced decreases in menopause-related symptoms and temporal high-frequency brain electrical activity with a noninvasive…
Meeting News Coverage

Risk for venous thrombotic events no higher in men with hypogonadism on testosterone therapy

March 11, 2015
SAN DIEGO — Men with hypogonadism do not appear to have any increased risk for venous thrombotic events with exogenous testosterone replacement…
Meeting News Coverage

Depression rates high among men referred for borderline testosterone

March 11, 2015
SAN DIEGO — Men who are referred for borderline testosterone levels have higher rates of depression and depressive symptoms compared with the…
Rocio Pereira Meeting News Coverage

Timing of estradiol therapy after menopause linked to insulin action

March 8, 2015
SAN DIEGO — Estradiol increased glucose disposal rate among women who were in the last 6 years of menses, according to study findings presented…
Meeting News Coverage

Longer estrogen treatment activates working memory in young postmenopausal women

March 8, 2015
Unique processing strategies for working memory may be implemented by estrogen treatment in older postmenopausal women, according to study findings…
Khalid Benkhadra Meeting News Coverage

Mortality risks remain unchanged with menopausal hormone therapy

March 7, 2015
SAN DIEGO — Menopausal hormone therapy does not appear to significantly alter the risk for all-cause mortality, or deaths related to…
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