Diabetes

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Gastrointestinal adverse events mild after therapy with GLP-1 receptor agonists

April 27, 2017

Patients with type 2 diabetes experienced gastrointestinal events less frequently when treated with a once-weekly dose of the glucagon-like peptide-1 receptor agonist exenatide than a twice-daily dose of exenatide or liraglutide, according to findings published in Diabetes, Obesity and Metabolism.

“GLP-1 [receptor agonists] have been shown to reduce HbA1c and body weight, with low intrinsic risk of hypoglycemia,” the researchers wrote. “One potential [adverse event] associated with these agents is an increase in gastrointestinal events that is transient in most cases. As such, understanding the specific gastrointestinal [adverse event] profile and how it varies across the GLP-1 [receptor agonist] class is of interest for patients and physicians and may be useful in guiding therapy.”

In the Journals Plus

Type 2 diabetes increases risk for dementia conversion in patients with mild cognitive impairment

April 26, 2017
Adults with type 1 diabetes and mild cognitive impairment are twice as likely to develop dementia as those who have mild cognitive impairment without diabetes, according…
In the Journals Plus

Diabetes risk high in Filipino Americans without obesity

April 26, 2017
Compared with non-Hispanic white adults, American adults of Filipino descent face higher risk for diabetes at a nonobese BMI, according to findings published in the…
In the Journals

Younger adults experiencing more ischemic strokes, CV risk factors

April 26, 2017
Even with the decrease of stroke mortality rates in older adults, hospitalization rates for ischemic stroke and traditional stroke risk factors are on the rise in young…
CME

Practical Lipidology®: Volume 3, Number 2

This activity is supported by an educational grant from Amgen

The reduction of low-density lipoprotein-cholesterol (LDL-C) is recognized as the primary strategy for decreasing…
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The Endocrine Society Annual Meeting

The Endocrine Society Annual Meeting

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Improving Bone Strength and Reducing Fracture Risk in Osteoporosis

This activity is supported by an educational grant from Merck & Co., Inc.

Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue leading to reduced…
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In the Journals Plus

Gastrointestinal adverse events mild after therapy with GLP-1 receptor agonists

April 27, 2017
Patients with type 2 diabetes experienced gastrointestinal events less frequently when treated with a once-weekly dose of the glucagon-like peptide-1…

In the Journals Plus

Type 2 diabetes increases risk for dementia conversion in patients with mild cognitive impairment

April 26, 2017
Adults with type 1 diabetes and mild cognitive impairment are twice as likely to develop dementia as those who have mild cognitive impairment without…

In the Journals Plus

Diabetes risk high in Filipino Americans without obesity

April 26, 2017
Compared with non-Hispanic white adults, American adults of Filipino descent face higher risk for diabetes at a nonobese BMI, according to findings…

In the Journals

Younger adults experiencing more ischemic strokes, CV risk factors

April 26, 2017
Even with the decrease of stroke mortality rates in older adults, hospitalization rates for ischemic stroke and traditional stroke risk factors are…

In the Journals Plus

Childhood obesity quadruples risk for type 2 diabetes

April 25, 2017
Compared with children with normal weight, children with obesity are four times more likely to develop incident type 2 diabetes before reaching…

In the Journals Plus

Lower hypoglycemia rates observed with iDegLira combination vs. basal insulins

April 25, 2017
In adults with type 2 diabetes, treatment with a fixed combination of insulin degludec and liraglutide resulted in lower rates of hypoglycemia…

In the Journals

Psoriatic arthritis linked with diabetes, other endocrine disorders

April 25, 2017
Psoriatic arthritis was linked with diabetes, Cushing disease, hypothyroidism and osteoporosis, according to a recent analysis of Israeli patients…

In the Journals Plus

Body fat, lean mass percentages associated with HbA1c in adults without diabetes

April 24, 2017
In adults without diabetes, increased percentages of total and trunk body fat were associated with an increased likelihood of an HbA1c in the…

In the Journals Plus

Maternal type 1 diabetes influences adiponectin, leptin levels in adolescent offspring

April 21, 2017
Adolescent girls born to mothers with type 1 diabetes have lower levels of adiponectin compared with adolescent girls born to mothers without…

In the Journals Plus

Starting metformin reduces risks for CV events, death in type 2 diabetes

April 20, 2017
The risks for cardiovascular events and death are decreased 6 months after metformin initiation among adults with type 2 diabetes who experience a…

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