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Hip, other fracture risk related to subclinical hyperthyroidism

May 26, 2015

An increased risk for hip and other fractures was found in patients with subclinical hyperthyroidism, especially among those with thyroid-stimulating hormone levels less than 0.1 mIU/L, but no association was found with subclinical hypothyroidism, according to recent study findings published in JAMA.

“Current guidelines recommend that treatment of subclinical hyperthyroidism should be strongly considered if TSH is persistently lower than 0.1 mIU/L in all individuals aged 65 years of older and that treatment should also be considered if TSH is low but at least 0.1 mIU/L in individuals who are at least 65 years old,” the researchers wrote. “Our results from pooling data of all available prospective cohorts, showing increased fracture risk in subclinical hyperthyroidism with even higher risk for participants with TSH levels of less than 0.1 mIU/L, are consistent with these recommendations.”

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