Bone/Mineral Metabolism

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Vitamin K antagonists do not affect bone mineral density, fracture risk

September 2, 2015

Vitamin K antagonists do not increase the risk for fracture or reduce bone mineral density, according to findings published in the Journal of Thrombosis and Haemostasis.

“Because osteocalcin, a protein produced by osteoblasts, undergoes the same carboxylation process [as vitamin K], the inhibition of the gamma-carboxylation exerted by vitamin K antagonists leads to lower incorporation in the bone matrix,” the researchers write. “Undercarboxylated osteolcalcin serum levels increase with the use of vitamin K antagonists, but whether this translates into fracture risk or lower bone mineral density values is still controversial.”

In the Journals

Proton pump inhibitors may increase fracture risk in older women

September 2, 2015
Older women who use proton pump inhibitors to reduce stomach acid may increase their risk for fracture, according to research in Bone.In a prospective cohort study…
In the Journals

Growth hormone reduces osteoporotic fracture risk in older women

August 28, 2015
Older women with osteoporosis treated with growth hormone showed a reduced risk for fracture and improved bone density that continued for years after stopping treatment…
In the Journals

Periostin levels higher in postmenopausal women with osteoporotic fracture

August 25, 2015
Plasma periostin levels may be a biomarker for osteoporotic fracture risk, particularly for fractures in limbs and other non-spinal sites, according to research in…
CME
Avoiding “Loss of Chance”…Improving the Screening, Treatment, and Referral of Patients with Diabetic Retinopathy

Avoiding “Loss of Chance”…Improving the Screening, Treatment, and Referral of Patients with Diabetic Retinopathy

This activity is supported by an educational grant from Genentech, Inc.

Despite a number of effective treatment options, diabetic eye disease is a leading cause of vision loss in the United…
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Meeting News Coverage Video
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VIDEO: New advances in bone biology related to energetics of the skeleton

March 8, 2015
SAN DIEGO — Clifford J. Rosen, MD, of Maine Medical Center Research Institute in Scarborough, Maine, discusses…
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CME
Obesity Consults

Obesity Consults: Volume 2, Number 5
Practical Guide to Medications Approved for Chronic Weight Management

This activity is supported by educational grants from Eisai, Inc. and Vivus, Inc.

Several pharmacologic options for the management of obesity have been approved by the US FDA, giving clinicians a range…
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Vitamin K antagonists do not affect bone mineral density, fracture risk In the Journals

Vitamin K antagonists do not affect bone mineral density, fracture risk

September 2, 2015
Vitamin K antagonists do not increase the risk for fracture or reduce bone mineral density, according to findings published in the Journal of
In the Journals

Proton pump inhibitors may increase fracture risk in older women

September 2, 2015
Older women who use proton pump inhibitors to reduce stomach acid may increase their risk for fracture, according to research in Bone.In a…
In the Journals

Growth hormone reduces osteoporotic fracture risk in older women

August 28, 2015
Older women with osteoporosis treated with growth hormone showed a reduced risk for fracture and improved bone density that continued for years after…
In the Journals

Periostin levels higher in postmenopausal women with osteoporotic fracture

August 25, 2015
Plasma periostin levels may be a biomarker for osteoporotic fracture risk, particularly for fractures in limbs and other non-spinal sites, according…

New test may detect osteoporosis, bone cancer in real-time

August 23, 2015
A geochemical assay that can measure sensitive calcium isotope ratios is currently in development by researchers and NASA scientists in the hopes of…
In the Journals

Vitamin D supplements may reduce falls in older homebound adults

August 18, 2015
A vitamin D intervention delivered through a Meals-on-Wheels program improved vitamin D concentrations in older adults who were homebound, while also…
In the Journals

Daily PrEP lowers hip, spine BMD in HIV-seronegative patients

August 17, 2015
Researchers found a small but statistically significant decrease in bone mineral density in the hip and spine for HIV-seronegative patients taking…
In the Journals

Increased DPP-IV activity predicts osteoporosis in postmenopausal women

August 14, 2015
Increased plasma DPP-IV activity is independently associated with osteoporosis in postmenopausal women with normal glucose tolerance, according to…
In the Journals

Resistance, jump training increased BMD in men

August 13, 2015
Bone mineral density of the whole body and lumbar spine in men with low bone mass was increased with resistance training and jump training…
In the Journals

Bone marrow toxicity limited in most patients after radioiodine therapy for DTC

August 12, 2015
Long-term bone marrow function is not compromised after radioiodine treatment for thyroid cancer, according to research in The Journal of Clinical
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