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Clinical practice guideline published for Paget's disease diagnosis, treatment

November 20, 2014

A clinical practice guideline for the diagnosis and treatment of Paget’s disease of the bone has recently been released by the Endocrine Society and has been subsequently published online in The Journal of Clinical Endocrinology and Metabolism.

The guidelines were developed by an Endocrine Society Task Force that included experts, a methodologist and a medical writer. The GRADE system was used to describe the strengths of the recommendations as well as the quality of evidence.

Borge Nordestgaard In the Journals

Increased mortality linked to genetically low vitamin D

November 19, 2014
Recent study findings suggest an association between low 25-hydroxyvitamin D concentrations and all-cause mortality, cancer mortality and other mortality, but not…
In the Journals

Denosumab may be useful in treating bisphosphonate-resistant hypercalcemia of malignancy

November 19, 2014
In patients with cancer and hypercalcemia of malignancy that persists despite treatment with intravenous bisphosphonates, denosumab appears to represent a valid…
Tamara Rozental In the Journals

Osteoporosis evaluation rates after distal radial fractures 'unacceptable' in older men

November 18, 2014
Fewer men than women were evaluated for osteoporosis after a distal radial fracture, with evaluation rates unacceptably low based on published guidelines, according to…
CME
Experts Take: Dialogue on HTG

Experts’ Take: Dialogue on Hypertriglyceridemia

This activity is supported by an independent educational grant from Amarin Pharma Inc.

Lead by genetic studies, recent data describe a causal role of triglycerides (TG) in the formation of atherosclerosis…
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CME
Acromegaly: Challenges in Diagnosis - Part 2 of 5

Acromegaly: Challenges in Diagnosis - Part 2 of 5

This activity is supported by an educational grant from Genentech.

The diagnosis of acromegaly is often not made until 7 to 10 years after symptom onset. Contributing factors include low…
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In the Journals

Clinical practice guideline published for Paget's disease diagnosis, treatment

November 20, 2014
A clinical practice guideline for the diagnosis and treatment of Paget’s disease of the bone has recently been released by the Endocrine…
Borge Nordestgaard In the Journals

Increased mortality linked to genetically low vitamin D

November 19, 2014
Recent study findings suggest an association between low 25-hydroxyvitamin D concentrations and all-cause mortality, cancer mortality and other…
In the Journals

Denosumab may be useful in treating bisphosphonate-resistant hypercalcemia of malignancy

November 19, 2014
In patients with cancer and hypercalcemia of malignancy that persists despite treatment with intravenous bisphosphonates, denosumab appears to…
Tamara Rozental In the Journals

Osteoporosis evaluation rates after distal radial fractures 'unacceptable' in older men

November 18, 2014
Fewer men than women were evaluated for osteoporosis after a distal radial fracture, with evaluation rates unacceptably low based on published…
Margaret Gourlay In the Journals

Frequent BMD tests unnecessary for younger postmenopausal women with good scores

November 14, 2014
Postmenopausal women not diagnosed for osteoporosis on an initial bone mineral density test are unlikely to sustain a major osteoporotic fracture or…
In the Journals

Body composition in childhood influenced bone strength, potentially fractures

November 3, 2014
The relationship between bone strength and fat mass may differ at weight-bearing compared with nonweight-bearing sites in children and adolescents…
In the Journals

Zoledronic acid discontinuation safe for some women after 3 years

October 27, 2014
Women who demonstrate a total hip T-score above –2.5 with no recent incident fracture and no more than one risk factor after 3 years on…

Unexpected vertebral fractures

October 24, 2014
Steve (not his real name) presented to the clinic with a recent history of vertebral fractures. He is 68 inches tall, weighs in at 170 lb., with a…
Peter Ebeling In the Journals

New report highlights osteoporosis prevalence in men, calls for action

October 14, 2014
Representing one-third of hip fractures worldwide, men have mortality rates as high as 37% in the first year following fracture, doubling…

Survey: Fewer than half of postmenopausal women take bone health supplements

October 12, 2014
A recent survey conducted by AIDP Inc. found that although women are well aware of the risks of brittle bones and fractures, fewer than half take…
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