Top Story

Congenital adrenal hyperplasia therapy granted orphan drug status

January 18, 2015

The FDA has granted orphan drug status to Neurocrine Biosciences, Inc., for NBI-77860, a proprietary corticotropin releasing factor 1 receptor antagonist for the treatment of congenital adrenal hyperplasia.

“We are very pleased that the FDA has granted NBI-77860 orphan status to treat congenital adrenal hyperplasia, a devastating disease that is a significant challenge for both clinicians and patients,” Malcolm Lloyd-Smith, chief regulatory officer or Neurocrine Biosciences, said in the release.

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CME
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This activity is supported by an educational grant from the American Beverage Association.

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FDA News

Congenital adrenal hyperplasia therapy granted orphan drug status

January 18, 2015
The FDA has granted orphan drug status to Neurocrine Biosciences, Inc., for NBI-77860, a proprietary corticotropin releasing factor 1 receptor…
In the Journals

Cushing's syndrome subtype affects postoperative time to adrenal recovery

January 16, 2015
In patients undergoing curative surgical tumor resection for Cushing’s syndrome, the time to recovery of adrenal function is contingent upon…
J. Josh Snodgrass In the Journals

Cortisol level changes linked to intimate partner violence in women

December 30, 2014
Higher levels of physical victimization in women were linked to higher levels of cortisol in midday and less linear decline throughout the day…
In the Journals

Mild adrenal steroidogenic defects common in patients with high BP

December 26, 2014
Mild defects of adrenal steroidogenesis occur in nearly half of patients with high blood pressure, according to research published in the…

Neurocrine Biosciences launches trial for congenital adrenal hyperplasia therapy

December 21, 2014
After completing a pilot clinical trial in adults with classic congenital adrenal hyperplasia, Neurocrine Biosciences, Inc. announced a…
In the Journals

High rates of adrenal crisis seen in patients with chronic insufficiency

December 8, 2014
Adrenal crisis occurs in a large proportion of patients with chronic adrenal insufficiency, even if they are educated about managing the disease…
In the Journals

Need for hydrocortisone linked to negative disease perception among adrenal-insufficient patients

October 3, 2014
In patients with adrenal insufficiency, strong beliefs about the necessity of hydrocortisone replacement and concerns about its adverse effects are…

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July 22, 2014
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Industry News

U.S. News & World Report announces top hospitals for endocrinology and diabetes care

July 15, 2014
Mayo Clinic and Cleveland Clinic garnered top honors among hospitals for diabetes and endocrinology-related care, as announced today in U.S. News
Meeting News CoveragePerspective

Smartphone-based immunoassay successfully measured salivary cortisol

June 26, 2014
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