Adrenal

Top Story

Moxonidine therapy useful option for primary aldosteronism screening

March 22, 2017

In healthy, normotensive men, treatment with moxonidine therapy for 6 weeks resulted in a decrease in blood pressure without altering the aldosterone-to-renin ratio, minimizing the risk for false-positive results in screening for primary aldosteronism, according to findings from researchers in Australia.

“Currently, the most popular screening test for [primary aldosteronism] is the plasma aldosterone-to-renin ratio (ARR),” Ashraf H. Ahmed, MBBS, MSc, PhD, of the endocrine hypertension research center at the University of Queensland School of Medicine, and colleagues wrote. “Although considered the most reliable available screening approach, the ARR is not without false positives or negatives. ... Because most antihypertensive medications are known to affect the ARR, it is often necessary to withdraw such interfering agents to enable confident interpretation of results. ... The identification of additional medications that are free of appreciable effects on the ARR would therefore be very worthwhile.”

In the Journals PlusPerspective

Postoperative ACTH, cortisol levels may predict Cushing’s disease remission rate

March 20, 2017
Early and midterm nonremission after transsphenoidal surgery in people with Cushing’s disease may be predicted by normalized early postoperative values for…
In the Journals Plus

Scalp hair cortisol accurate in Cushing’s syndrome diagnosis

March 20, 2017
Scalp hair cortisol measurement is an accurate first-line diagnostic test for Cushing’s syndrome in adults and offers several advantages over other first-line…
In the Journals Plus

Height in congenital adrenal hyperplasia improves with low hydrocortisone dose

March 2, 2017
Height outcome in children with congenital adrenal hyperplasia may be improved with a low hydrocortisone dose and use of mineralocorticoid therapy, according to findings…
CME

Practical Lipidology®: Volume 3, Number 1

This activity is supported by an educational grant from Amgen

The reduction of low-density lipoprotein-cholesterol (LDL-C) is recognized as the primary strategy for decreasing…
More »
Video
Meeting News Coverage

Vlog: Global endocrinology community gathers for ICE/ENDO 2014

June 21, 2014
More »
Featured
ObesityWeek

ObesityWeek

CME

Improving Bone Strength and Reducing Fracture Risk in Osteoporosis

This activity is supported by an educational grant from Merck & Co., Inc.

Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue leading to reduced…
More »
In the Journals Plus

Moxonidine therapy useful option for primary aldosteronism screening

March 22, 2017
In healthy, normotensive men, treatment with moxonidine therapy for 6 weeks resulted in a decrease in blood pressure without altering the…

In the Journals PlusPerspective

Postoperative ACTH, cortisol levels may predict Cushing’s disease remission rate

March 20, 2017
Early and midterm nonremission after transsphenoidal surgery in people with Cushing’s disease may be predicted by normalized early…

In the Journals Plus

Scalp hair cortisol accurate in Cushing’s syndrome diagnosis

March 20, 2017
Scalp hair cortisol measurement is an accurate first-line diagnostic test for Cushing’s syndrome in adults and offers several advantages over…

In the Journals Plus

Height in congenital adrenal hyperplasia improves with low hydrocortisone dose

March 2, 2017
Height outcome in children with congenital adrenal hyperplasia may be improved with a low hydrocortisone dose and use of mineralocorticoid therapy…

In the Journals Plus

Congenital adrenal hyperplasia tied to overweight, obesity risk

February 24, 2017
Children with congenital adrenal hyperplasia have an increased risk for overweight or obesity compared with healthy children, but rates of persistent…

In the Journals Plus

Age, insurance status related to hospitalization for children with congenital adrenal hyperplasia

February 17, 2017
Among children with congenital adrenal hyperplasia, those who are younger and those with government insurance may be at increased risk for…

In the Journals PlusPerspective

Previous cancer affects future cancer incidence, mortality risk with pediatric GH therapy

February 17, 2017
In patients with previous cancers treated with recombinant human growth hormone therapy as children, researchers observed increased risks for both…

In the Journals PlusPerspective

Hair analysis may identify Cushing’s syndrome

February 16, 2017
The use of a hair analysis to measure cortisol levels may be an effective initial or supportive test for signaling Cushing’s syndrome…

In the Journals Plus

Fracture risk, severity higher in patients with primary aldosteronism

February 14, 2017
Patients with primary aldosteronism are more likely to sustain a vertebral fracture compared with healthy age- and sex-matched controls, according to…

Genetic profile of rare adrenal disorder may diminish gender ambiguity

February 5, 2017
Researchers at the Icahn School of Medicine at Mt. Sinai have developed a clinical and genetic profile of steroid 11-hydroxylase deficiency, a rare…

More Headlines »
Advertisement
Advertisement