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Saxenda linked to reduced body weight, improved metabolic control

Saxenda linked to reduced body weight, improved metabolic control
July 2, 2015

Reduced body weight and improved metabolic control were found with once-daily subcutaneous Saxenda as an add-on to diet and exercise, according to recent study findings published in The New England Journal of Medicine.

Xavier Pi-Sunyer, MD, of Columbia University Medical Center, and colleagues conducted a 56-week, double blind study to evaluate 3,731 patients aged 18 years or older without type 2 diabetes and a BMI of at least 30 kg/m2 or a BMI of at least 27 kg/m2 if they had treated or untreated dyslipidemia or hypertension to determine the effect of Saxenda (liraglutide, Novo Nordisk) on weight management. Participants were randomly assigned to 3 mg once-daily subcutaneous liraglutide (n = 2,487) or placebo (n = 1,244) with counseling on lifestyle modification. Change in body weight and rate of patients losing at least 5% and more than 10% of their initial body weight were the primary endpoints.

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