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Personalized vaccines provoke antitumor activity in melanoma

Personalized vaccines provoke antitumor activity in melanoma
May 27, 2015

A dendritic cell vaccine targeted at patient-specific neoantigens expanded the antitumor immune response in patients with melanoma, according to study results.

“Neoantigens are like flags on a cancer cell, calling attention to the immune system,” Beatriz M. Carreno, PhD, of the division of oncology at Washington University School of Medicine, said during a press conference. “In any one patient with melanoma, there can be hundreds of flags on tumors. The challenge presented to us was how to identify the unique flags that were more likely to elicit a strong immune response against the tumor.”

In the Journals

Female-to-male transgender patients experience severe acne

May 27, 2015
Researchers have reported two cases of severe acne in female-to-male transgender patients whose symptoms required continuous therapy with isotretinoin.The first was a…
In the Journals

Study: Poly-L-lactic acid improved hill and valley acne scarring

May 26, 2015
Injectable poly-L-lactic acid treatment improved hill and valley acne scarring and was well-tolerated by patients, according to study results.In a single-arm, unblinded…

Amgen to terminate participation in co-development of brodalumab

May 26, 2015
Amgen announced that it has commenced terminating its participation in the co-development and commercialization of brodalumab with AstraZeneca for treating…
In the Journals

Radiofrequency microneedling treats periorbital wrinkles in dark-skinned patients safely

May 26, 2015
Use of a fractional radiofrequency microneedle system on Korean patients improved periorbital wrinkles according to two independent experts and patient satisfaction…
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Video
VIDEO: Does a non-surgical facelift exist?

VIDEO: Does a non-surgical facelift exist?

May 17, 2015
MONTREAL — Laurie Casas, MD, describes how you can be an internist for facial aging for your patients at The…
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Meeting News Coverage Video
Update on evaluating rashes, eosinophilia in pediatric travelers

Update on evaluating rashes, eosinophilia in pediatric travelers

April 27, 2015
SAN DIEGO — Lawrence F. Eichenfield, MD, chief of pediatric and adolescent dermatology at Rady Children's…
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Meeting News Coverage Video
VIDEO: Speaker reviews new technology for noninvasive body contouring

VIDEO: Speaker reviews new technology for noninvasive body contouring

April 16, 2015
SAN FRANCISCO — In this video, Arisa Ortiz, MD, discusses the latest developments in devices for noninvasive body…
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